Table 4.
Race-stratified Lp(a)-related risk of developing CHD over a 12-year follow-up period.a
| Lp(a)-M (mg/dL) | Lp(a)-C (mg/dL) | Lp(a)-P (nmol/L) | |
|---|---|---|---|
| Black | |||
| Upper 15th% cutoff value | 83.9 | 9.9 | 167 |
| Estimated HR | 2.01 | 1.92 | 1.59 |
| 95% CI | (1.22–3.30) | (1.16–3.18) | (0.95–2.66) |
| P value | 0.006 | 0.01 | 0.08 |
| White | |||
| Upper 15th% cutoff value | 49.3 | 5.7 | 102 |
| Estimated HR | 1.45 | 1.55 | 1.53 |
| 95% CI | (0.95–2.24) | (1.01–2.38) | (1.01–2.32) |
| P value | 0.09 | 0.05 | 0.05 |
| Chinese-American | |||
| Upper 15th% cutoff value | 36.2 | 3.0 | 62 |
| Estimated HR | 2.54 | 2.43 | 2.02 |
| 95% CI | (1.05–6.16) | (1.02–5.78) | (0.82–4.96) |
| P value | 0.04 | 0.04 | 0.13 |
| Hispanic | |||
| Upper 15th% cutoff value | 46.0 | 4.6 | 93 |
| Estimated HR | 1.69 | 1.14 | 1.04 |
| 95% CI | (0.92–3.08) | (0.59–2.18) | (0.54–2.00) |
| P value | 0.09 | 0.70 | 0.91 |
a
Hazard ratios (HRs)and 95% CI are presented for individuals in upper 15th percentiles for each Lp(a) marker. Adjustments were made for age, sex, hypertension, smoking, education status, diabetes, LDL-C, and HDL-C. Upper 15th percentile cutoff values are shown for each analyte within each racial/ethnic group.