Fig 7. Switch between SMRT and NCoR.

(A) ChIP assay for SMRT and NCoR interaction with NF-kB association. This result was obtained in the same condition as for ChIP assay of SRC-1. (B) Cotransfection of SMRT or NCoR with IkBα reporter. The IkBα reporter was activated by cotransfection of p65 and p50 expression vectors, which was used at 0.1 μg/point for each vector. Plasmid DNA (μg) for SMRT or NCoR is indicated. (C) Knockdown of SMRT or NCoR by vector-based RNAi expression. Vector DNA (μg) of RNAi expressing plasmid is indicated.