TABLE 2.

Baseline and Percent Change From Baseline Lipid and Apolipoprotein Values

	Placebo			Ezetimibe 10 mg/d
Sterol or Apolipoprotein	Baseline Mean, mmol/L	% Change (SE)	95% CI for % Change	Baseline Mean, mmol/L	% Change (SE)	95% CI for % Change	Between-Group Difference (95% CI)
Sitosterol	0.44	4.0 (5.3)	−6.9 to 14.8	0.50	−21.0 (2.8)	−26.7 to −15.3	325.0 (−36.7 to −13.6)
Campesterol	0.23	3.2 (5.5)	−7.9 to 14.3	0.27	−24.3 (2.9)	−30.7 to −18.4	−27.5 (−39.6 to −15.4)
Lathosterol	0.012	−7.2 (5.1)	−20.2 to 5.9	0.007	10.6 (6.1)	−1.9 to 23.2	17.8 (−7.9 to 43.4)
LDL-C*	2.31	16.7 (19.7)	−31.6 to 64.9	2.47	−13.6 (4.0)	−21.7 to −5.5	NA
LDL sterols	3.11	18.4 (7.7)	2.8 to 34.0	3.39	−14.9 (4.1)	−23.2 to −6.6	−33.3 (−50.4 to −16.2)
HDL sterols	1.27	5.5 (5.0)	−4.7 to 15.7	1.42	2.2 (2.6)	−3.2 to 7.6	−3.3 (−14.4 to 7.8)
HDL-C (GC)	0.86	8.3 (6.1)	−4.2 to 20.7	1.03	6.2 (3.2)	−0.4 to 12.8	−2.1 (−15.6 to 11.5)
Cholesterol (GC)	3.75	8.0 (6.1)	−11.3 to 27.3	4.35	−4.8 (3.2)	−14.9 to 5.3	−12.8 (−26.4 to 0.7)
Total sterols	5.29	3.7 (4.8)	−6.2 to 13.5	5.62	−8.7 (2.5)	−13.9 to −3.5	−12.4 (−23.1 to −1.7)
Triglyceride*	2.2	−20.8 (6.9)	−37.6 to −4.0	1.66	−2.1 (8.1)	−18.7 to 14.6	NA
Apo A-I (mg/dL)	146.7	0.6 (4.2)	−7.9 to 9.2	159.0	6.5 (2.2)	2.0 to 11.0	5.9 (−3.4 to 15.2)
Apo B (mg/dL)	128.2	3.1 (4.5)	−6.1 to 12.2	129.9	−12.7 (2.4)	−17.5 to −7.9	−15.8 (−25.8 to −5.8)
Lath:Chol ratio	0.41	−7.2 (11.2)	−30.1 to 15.8	0.18	10.6 (5.6)	−0.8 to 22.1	37.3 (1.0 to 73.7)

Apo indicates apolipoprotein; GC, gas chromatography; and Lath:Chol, lathosterol:cholesterol.

^*LDL-C and triglyceride results presented as median, given nonnormal distribution of results, and hence, between-group differences are not provided.