Fig. 4.

Taxol-induced changes of distribution of endocytosed L1 in growth cones migrating on L1. Endocytosed L1 at the 30 min time points was visualized as shown in Figure 3,D and E. A total of 60 taxol-treated growth cones and 45 DMSO control growth cones were analyzed, and the number of L1-positive endocytic organelles in the P-domain was categorized into four groups. Shown are the percentages of growth cones in each group. There was a statistically significant difference between the taxol-treated and control growth cones (p < 0.0001).