FIG. 1.
Mouse Insm1 cDNA. (A) Analysis of the deduced amino acid sequence of mouse INSM1. The longest clone was 2909 bp and contained an ORF encoding a protein of 521 amino acids. The deduced protein sequence of mouse INSM1 is characterized by a SNAG motif (blue, amino acids 1–7), three proline-rich sequences (green, amino acids 43–57, amino acids 75–85, and amino acids 405–414) and five C2H2 zinc-finger motifs (yellow). A NLS sequence (amino acids 350–367) is shown in red. Two polyadenylation consensus sequences (dashed lines) are seen in the 3′-untranslated region. (B) Diagrammatic representation of mouse INSM1. SNAG motif, proline-rich regions, five zinc-finger motifs, and an NLS are shown.