TABLE 2.
NHLBI Programs in Genomics Applications
| Name | Project Title | Project Web Site | Resources |
|---|---|---|---|
| BayGenomics | The NHLBI-Bay Area Functional Genomics Consortium | http://baygenomics.ucsf.edu/ | Murine embryonic stem cell lines for use in cardiovascular and pulmonary research |
| Berkeley PGA | Comparative Genomic Analysis of Cardiovascular Gene Regulation | http://pga.lbl.gov | VISTA tools for comparative genomics; CVCGD database of cardiovascular genes; NOMAD microarray database |
| CardioGenomics | Genomics of Cardiovascular Development, Adaptation and Remodeling | http://www.cardiogenomics.org | Expression profiles from murine models of cardiomyopathy; sarcomere protein gene mutation database; human gene mutation and SNP data |
| HopGenes | Applied Genomics in Cardiopulmonary Disease | http://www.hopkins-genomics.org | affynoRM A microarray analysis software; cardiopulmonary disease candidate genes list; expression profiles from rat and murine models of pulmonary disease |
| InnateImmunity | Innate Immunity in Heart, Lung, and Blood Disease | http://innateimmunity.net | Innate immunity gene list; SNP data analysis tools |
| JAX PGA | Mouse Models of Heart, Lung, and Blood Diseases | http://pga.jax.org | Murine models of heart, lung, blood, and sleep disorders, mouse phenome database |
| ParaBioSys | Genomic Analysis of Stress and Inflammation | http://pga.mgh.harvard.edu | ParaBioSys software tools for genomic searching and alignment; murine expression data in response to proinflammatory, metabolic, and pathogen stresses affecting the cardiovascular system and the lung |
| PhysGen | Physiogenomics of Stressors in Derived Consomic Rats | http://pga.mcw.edu | Consomic rat strains for investigating physiological mechanisms of homeostasis and response to stress; phenotypic, genotypic, and microarray data |
| Seattle SNPs | UW-FHCRC Variation Discovery Resource | http://pga.mbt.washington.edu | Human inflammatory response SNP database; PolyPhred SNP detection software; Genotype (VG2) and Haplotype (VH1) visualization software |
| Southwestern | Genomics and Proteomics of Cell Injury and Inflammation | http://pga.swmed.edu | Expression and SNP data on genes involved in the cellular response to injury an inflammation; GeneTraffic microarray database |
| TREX | Microarray Expression Profiling of Rodent Models of Human Disease | http://pga.tigr.org | TIGR Microarray Data Analysis System; expression profiles for murine and rat models of heart, lung, and blood disease |