Table 2.
Control group | ΔCt | mRNA level (×1,000) | Schizophrenia group | ΔCt | mRNA level (×1,000) |
---|---|---|---|---|---|
1 | 10.49 | 0.69 | 1 | 9.02 | 1.92* |
2 | 10.76 | 0.57 | 2 | 10.03 | 0.95 |
3 | 10.23 | 0.83 | 3 | 8.64 | 2.51 |
4 | 10.82 | 0.55 | 4 | 9.71 | 1.19 |
5 | 11.46 | 0.35 | 5 | 9.35 | 1.53 |
6 | 10.45 | 0.71 | 6 | 8.92 | 2.06* |
7 | 11.84 | 1.27 | 7 | 9.25 | 1.64 |
8 | 8.96 | 2.01 | 8 | 8.88 | 2.12* |
9 | 9.71 | 1.19 | 9 | 8.33 | 3.11 |
10 | 9.16 | 1.74 | 10 | 8.67 | 2.45 |
11 | 9.52 | 1.36 | 11 | 8.59 | 2.59 |
12 | 10.60 | 0.64 | 12 | 8.68 | 2.43 |
13 | 10.30 | 0.79 | 13 | 9.47 | 1.41 |
14 | 11.06 | 0.47 | 14 | 9.96 | 1.00 |
15 | 9.35 | 1.53 | 15 | 8.51 | 2.74 |
Av | 10.31 | 0.91 | Av | 9.06 | 1.97 |
The ΔCt value was derived by normalizing mRNA transcript levels against the housekeeping gene GAPDH. Each ΔCt was produced by the mean values taken for two independent replicates. Note that a higher ΔCt value indicates lower expression levels (a ΔCt decrease of 1 corresponds to a 2-fold increase in gene expression). The mRNA level value was obtained by the equation 2−ΔCt.
denotes schizophrenia patients who were not treated with antipsychotics at time of death.