Fig. 2.

Viability of adult S. mansoni worms during exposure to clocinizine. Adult worm pairs were obtained from animals by perfusion 42 days post-infection. Each concentration of clocinizine was tested in triplicate, with the highest concentration of DMSO serving as the control and praziquantel (PZQ) at 2 µM used as the reference drug. Male and female schistosomes were monitored for up to 72 h. Results are expressed as percent mortality, represented by Kaplan-Meier survival curves. Data are presented as the mean ± SD from three independent experiments.