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Therapeutic efficacy of clocinizine in Schistosoma mansoni infection. S. mansoni-infected mice were orally administered a single dose of 400 mg/kg clocinizine or praziquantel 42 days post-infection. Vehicle (water) was administered to the control group. All mice were euthanized on day 56 post-infection. Parasite burdens, as well as intestinal and fecal egg counts, were quantified. Data are presented as the mean ± SD (n = 5). ***P < 0.0001 compared to the infected untreated control.
