Table 5.
Univariate and multivariable linear regression analysis of clinical and urodynamic parameters to predict the change of OABSS total score from baseline after 12 weeks of treatment.
| Variables | Univariate | Multivariable | ||||
|---|---|---|---|---|---|---|
| Coefficient | 95% CI | P† | Coefficient | 95% CI | P‡ | |
| Daytime vs. nighttime dosing (= 1) | 0.202 | − 1.112 to 1.514 | 0.760 | – | – | – |
| Age (years) | 0.198 | − 0.033 to 0.072 | 0.456 | 0.065 | 0.003 to 0.127 | 0.039 |
| Parity | − 0.122 | − 0.719 to 0.475 | 0.684 | – | – | – |
| Body mass index (kg/m2) | 0.072 | − 0.064 to 0.208 | 0.293 | – | – | – |
| OABSS (0–15) | − 0.337 | − 0.569 to − 0.105 | 0.005 | − 0.389 | − 0.633 to − 0.145 | 0.002 |
| Detrusor overactivity | − 0.062 | − 1.857 to 1.734 | 0.946 | – | – | – |
| Urodynamic stress incontinence | 0.678 | − 0.619 to 1.975 | 0.301 | 0.999 | − 0.326 to 2.323 | 0.137 |
| Pad weight (g) | − 0.0044 | − 0.0125 to 0.0036 | 0.278 | – | – | – |
| Qmax (mL/s) | 0.004 | − 0.046 to 0.054 | 0.874 | – | – | – |
| Voided volume (mL) | − 0.0005 | − 0.0053 to 0.0043 | 0.847 | – | – | – |
| Postvoid residual volume (mL) | − 0.003 | − 0.012 to 0.006 | 0.538 | − 0.006 | − 0.017 to 0.002 | 0.129 |
| PdetQmax (mmHg) | − 0.0004 | − 0.0330 to 0.0321 | 0.979 | – | – | – |
| MUCP (cmH2O) | − 0.0007 | − 0.0227 to 0.0213 | 0.952 | 0.020 | − 0.005 to 0.045 | 0.119 |
CI, confidence index. The other abbreviations are the same as in Table 1.
†Univariate linear regression analysis.
‡Multivariable backward stepwise linear regression analysis was performed using all variables in the univariate analysis until all remaining variables had a p < 0.25.