Table 3.

A list of 10 out of 16 drug-disease associations supported by shared genes/proteins and clinical trials.

No.	Drug ID (KEGG ID)	Drug Name	Disease ID (MIM ID)	Disease Name	Shared Genes (Entrez ID)	ClinicalTrials.gov (NCT ID)
1	D00059	Levodopa (JP18/USP/INN); Dopar (TN)	181,500	SCHIZOPHRENIA; SCZD	DRD3	NCT01636037
2	D00075	Testosterone (JAN/USP); Androderm (TN); Androgel (TN); Axiron (TN); Striant (TN); Testim (TN)	176,807	PROSTATE CANCER	AR	NCT04558866, NCT05081193, NCT01187485, NCT04424654, NCT03716739, NCT02286921, NCT03522064, NCT04363164, NCT00853697, NCT02090114, NCT01084759, NCT00515112, NCT04134130, NCT02995330, NCT01750398, NCT03554317, NCT03516812, NCT00587431, NCT01978873, NCT00586898, NCT00577980, NCT03734653, NCT05011383, NCT00006044, NCT00588185, NCT05530395, NCT02297386
3	D00181	Argatroban (USP); Argatroban hydrate (JP18); Novastan (TN)	601,367	STROKE, ISCHEMIC	F2	NCT03552354, NCT04275180, NCT00268762, NCT01464788, NCT03740958, NCT03735979, NCT04202549, NCT00153946, NCT02448069
4	D00400	Valsartan (JP18/USP/INN); Diovan (TN)	145,500	HYPERTENSION, ESSENTIAL	AGTR1	NCT01878201, NCT01001572, NCT01122251, NCT00922441, NCT02480764, NCT00437645, NCT02062645, NCT03371797, NCT00254475, NCT00446524, NCT00425373, NCT02058446, NCT01241487, NCT00716950, NCT00591578, NCT01672476, NCT00699192, NCT00696436, NCT02415192, NCT00546754, NCT00338936
5	D00426	Risperidone (JP18/USP/INN); Risperdal (TN)	164,230	OBSESSIVE-COMPULSIVE DISORDER; OCD	HTR2 A	NCT00389493, NCT05401019, NCT00854919
6	D00454	Olanzapine (JAN/USP/INN); Zyprexa (TN)	143,465	ATTENTION DEFICIT-HYPERACTIVITY DISORDER; ADHD	DRD4	NCT00205699, NCT01000402
7	D00522	Candesartan (USAN/INN)	145,500	HYPERTENSION, ESSENTIAL	AGTR1	NCT02368652, NCT01350609, NCT02368665, NCT01303783, NCT02944734, NCT01227603, NCT02059616, NCT01629225, NCT00608153, NCT02206165, NCT00573742, NCT01788358, NCT01135212, NCT02969265, NCT00644475, NCT02047019, NCT00607633, NCT00802542, NCT01289132, NCT00141583
8	D00559	Pramipexole dihydrochloride (USP); Pramipexole hydrochloride hydrate (JAN); Pramipexole dihydrochloride monohydrate; Mirapex (TN)	181,500	SCHIZOPHRENIA; SCZD	DRD3	NCT01320982
9	D01204	Olmesartan medoxomil (JP18/USP); Benicar (TN); Olmetec (TN)	145,500	HYPERTENSION, ESSENTIAL	AGTR1	NCT02848170, NCT00996281, NCT01599104, NCT02407210, NCT00872586, NCT01615198, NCT01785472, NCT00890591, NCT05033535, NCT00185172, NCT00430950, NCT00856271, NCT00139698, NCT00857285, NCT05110898, NCT00846365, NCT00430508, NCT00751751, NCT00311155, NCT00902538, NCT01033071, NCT01838850, NCT02495324, NCT00759551
10	D01441	Imatinib mesylate (USAN); Imatinib mesilate (JAN); Gleevec (TN); Glivec (TN)	601,626	LEUKEMIA, ACUTE MYELOID; AML	KIT	NCT00594555, NCT00171249, NCT00955916, NCT00088231, NCT01126814, NCT00509093, NCT00744081, NCT00451997, NCT00469014, NCT00268229, NCT00707408, NCT00258271, NCT00025415, NCT00004932, NCT00064285, NCT00171223, NCT02352558, NCT00298987, NCT00386373, NCT03878524