Table 5.
Experimentally verified target genes associated with differentially regulated miRNAs.
| miRNA(s) | Number of genes | Experimentally verified genes name |
|---|---|---|
| hsa-miR-30c-5p | 40 | SNAI1, SERPINE1, UBE2I, SMAD1, IL11, VIM, TWF1, MTA1, HSPA4, TGIF2, HDAC4, SOCS3, BCL9, DDIT4, DLL4, CCND2, IDH1, RARB, NCOR2, RFX6, CASP3, RUNX2, JAK1, MTTP, SNAI2, NOTCH1, TP53, FASN, EIF2S1, BECN1, DNMT1, RASAL2, CAMK2D, IER2, CDC42, PAK1, FOXO3, CTGF, MCL1, TRADD |
| hsa-miR-335-3p | 5 | NOS3, ESR1, PAX6SP1, MET, SP1 |
| hsa-miR-132-3p | 34 | ARHGAP32, SIRT1, CDKN1A, RB1, CRK, HBEGF, RASA1, TJAP1, TLN2, SPRED1, MUC13, CCNA2, CCNB1, FOXO1, JPT1, BDNF, KLHL11, MAPK1, SOX4, SOX5, IRAK4, EGFR, RAF1, SPRY1, MMP9, GDF5, YY1AP1, AGO2, PIK3R3, SOX6, SMAD2, SLC2A1, FOXO3, PTEN, |
| hsa-miR-127-3p | 18 | MAPK4, MMP13, PRDM1, XBP1, BCL6, KMT5A, XRCC3, SKI, SEPT7, RGMA, ZWINT, SFRP1, SERPINB9, MGMT, BAG5, IGF1R, IRS1, BLVRB |
| hsa-miR-103a-2-5p | 2 | SMAD4, PDCD10 |
| hsa-miR-146b-3p | 5 | PER1, MAT2A, NPAS4, IRAK1, SMAD4 |
| hsa-miR-202-5p | 3 | TGFBR1, TGFBR2, TNFSF13B |
| hsa-miR-18a-3p | 7 | KRAS, CBX7, ATM, HIF1α, IRF2, S6k1, 4EBPL |
| hsa-miR-154-5p | 6 | TLR2, ZEB2, HMGA2, CCND2, WNT5A, E2F5 |
| hsa-miR-28-3p | 2 | STAT5B, TP53, BAG1, IGF1 |