Table 3.
Means and Standard Deviations of QOL Items According to Treatment and Disease
| Chemotherapy
|
Local Therapy
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Breast Cancer (n = 141)
|
Lymphoma (n = 66)
|
Breast Cancer (n = 294)
|
Lymphoma (n = 37)
|
|||||||
| QOL Item | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Overall TX P* | TX × DX P |
| Physical well-being | ||||||||||
| Fatigue | 6.8 | 2.7 | 5.5 | 3.1 | 6.9 | 2.7 | 6.6 | 2.6 | .02 | |
| Aches/pain | 6.8 | 2.7 | 5.7 | 3.0 | 6.6 | 2.6 | 7.0 | 2.8 | .003 | |
| Overall physical health | 8.0 | 1.8 | 7.0 | 2.5 | 7.9 | 1.8 | 7.6 | 1.8 | .01 | |
| Appetite | 8.7 | 2.2 | 8.5 | 2.5 | 9.1 | 2.0 | 8.1 | 2.7 | .75 | |
| Sleep | 6.6 | 3.3 | 6.4 | 3.3 | 7.1 | 2.9 | 7.7 | 2.8 | .17 | |
| Constipation | 8.7 | 2.2 | 8.7 | 2.3 | 8.7 | 2.4 | 8.6 | 2.7 | .65 | |
| Nausea | 9.7 | 0.9 | 9.2 | 2.0 | 9.5 | 1.5 | 9.5 | 1.3 | .33 | |
| Menstrual fertility | 8.9 | 2.6 | 8.6 | 3.2 | 9.7 | 1.3 | 9.1 | 2.3 | .01 | |
| Psychological well-being | ||||||||||
| Concentration/memory | 7.0 | 2.2 | 6.7 | 2.5 | 7.5 | 1.8 | 7.4 | 2.1 | .19 | |
| Appearance | 6.7 | 3.2 | 7.1 | 3.5 | 7.6 | 3.3 | 8.1 | 2.6 | .04 | |
| CA treatment distress | 3.3 | 3.1 | 3.3 | 2.9 | 5.5 | 3.4 | 3.7 | 3.1 | < .004 | |
| Fear of future tests | 5.7 | 3.3 | 6.8 | 2.9 | 6.8 | 3.1 | 5.5 | 3.1 | .52 | |
| Fear spread of CA | 5.4 | 3.8 | 7.4 | 3.4 | 7.0 | 3.2 | 6.9 | 3.7 | .52 | |
| Coping | 8.6 | 2.2 | 8.2 | 2.7 | 9.0 | 1.9 | 8.7 | 2.2 | .19 | |
| QOL single item | 8.7 | 1.7 | 8.3 | 2.0 | 8.6 | 1.9 | 8.5 | 2.1 | .95 | |
| Happiness | 8.6 | 1.7 | 8.3 | 2.2 | 8.5 | 1.9 | 8.5 | 1.8 | .76 | |
| Control | 8.4 | 1.9 | 8.2 | 2.3 | 8.4 | 1.9 | 8.0 | 2.1 | .36 | |
| Satisfaction | 8.5 | 1.7 | 8.4 | 1.7 | 8.4 | 1.7 | 8.2 | 1.9 | .21 | |
| Usefulness | 8.6 | 1.6 | 8.2 | 1.9 | 8.4 | 1.9 | 8.1 | 2.2 | .29 | |
| Self-concept | 7.2 | 3.3 | 7.0 | 3.6 | 8.0 | 3.1 | 6.8 | 3.4 | .89 | |
| Initial DX distress | 1.5 | 2.7 | 2.3 | 3.3 | 2.7 | 3.3 | 1.3 | 2.2 | .77 | |
| Time since TX distress | 7.0 | 2.8 | 7.4 | 2.9 | 7.9 | 2.7 | 7.5 | 2.5 | .22 | |
| Anxiety | 6.1 | 2.9 | 6.3 | 3.3 | 6.1 | 2.8 | 6.0 | 3.1 | .34 | |
| Depression | 7.6 | 2.8 | 7.6 | 2.8 | 7.7 | 2.4 | 7.6 | 3.1 | .71 | |
| Fear second CA | 5.3 | 3.5 | 6.1 | 3.2 | 6.3 | 3.1 | 5.2 | 3.4 | .53 | |
| Fear recurrent CA | 5.3 | 3.6 | 6.7 | 3.3 | 6.6 | 3.1 | 6.3 | 3.4 | .70 | |
| Social well-being | ||||||||||
| Family distress | 3.4 | 3.0 | 3.6 | 3.5 | 5.0 | 3.2 | 4.2 | 3.1 | .11 | |
| Personal relationships | 9.1 | 2.2 | 9.0 | 2.4 | 9.5 | 1.8 | 9.2 | 2.2 | .09 | |
| Sexuality | 7.4 | 3.4 | 7.6 | 3.5 | 8.9 | 2.4 | 9.5 | 1.7 | .03 | |
| Home activities | 8.4 | 2.7 | 7.0 | 3.1 | 9.3 | 1.8 | 8.5 | 2.6 | .001 | |
| Feel isolated | 9.0 | 2.2 | 8.6 | 2.7 | 9.6 | 1.4 | 9.0 | 2.3 | .15 | |
| Financial burden | 7.3 | 3.2 | 6.7 | 3.7 | 8.7 | 2.3 | 7.6 | 3.0 | .01 | |
| Employment | 8.6 | 2.8 | 6.8 | 3.9 | 9.7 | 1.2 | 9.0 | 2.3 | .01 | |
| Support/others | 8.5 | 2.5 | 8.3 | 3.1 | 8.5 | 2.6 | 7.9 | 2.2 | .56 | |
| Spiritual well-being | ||||||||||
| Spiritual change | 6.7 | 2.9 | 6.6 | 2.7 | 6.4 | 2.7 | 5.9 | 2.9 | .28 | |
| Positive change | 6.1 | 3.5 | 4.9 | 4.1 | 4.5 | 3.9 | 4.8 | 2.7 | .13 | |
| Important religious activity | 6.7 | 3.8 | 6.0 | 4.0 | 6.6 | 3.8 | 5.3 | 3.7 | .26 | |
| Important spiritual activity | 4.6 | 4.1 | 4.4 | 4.2 | 4.4 | 4.0 | 2.8 | 3.4 | .27 | |
| Uncertainty | 4.1 | 3.3 | 3.9 | 3.3 | 3.2 | 3.0 | 4.3 | 3.0 | .64 | |
| Life purpose | 7.5 | 3.0 | 7.3 | 3.5 | 7.1 | 3.4 | 7.5 | 3.2 | .66 | |
| Hopefulness | 8.8 | 1.7 | 8.4 | 2.6 | 8.7 | 2.0 | 8.7 | 1.9 | .53 | |
Abbreviations: QOL, quality of life; TX, treatment; DX, diagnosis; SD, standard deviation; CA, cancer.
*
Adjusted for age at interview, time since last treatment, sex, diagnosis, education, and stage at diagnosis.