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. 2025 Aug 21;15:30801. doi: 10.1038/s41598-025-15875-z

Table 2.

Odds ratio for In-hospital mortality according to heart rate change.

Group No. of group No. of mortality Model 1a Model 2b Model 3c Model 4d
Odds ratio p-value p for trend Odds ratio p-value p for trend Odds ratio p-value p for trend Odds ratio p-value p for trend
high to high 3597 795 reference < 0.001 reference 0.650 reference 0.291 reference 0.311
high to low 49 10 0.810 (0.380–1.572) 0.557 0.848 (0.395–1.659) 0.649 0.989 (0.455–1.962) 0.9759 0.966 (0.443–1.920) 0.925
low to high 2008 475 1.039 (0.911–1.184) 0.564 1.336 (1.135–1.573) < 0.001 1.295 (1.093–1.533) 0.003 1.297 (1.094–1.538) 0.003
low to low 7821 1427 0.730 (0.661–0.806) < 0.001 1.050 (0.886–1.244) 0.574 1.104 (0.927–1.315) 0.268 1.099 (0.921–1.311) 0.296

a: adjusted for age, sex, new onset atrial fibrillation.

b: adjusted for age, sex, new onset atrial fibrillation, heart rate, systolic blood pressure, diastolic blood pressure, respiratory rate, saturation of percutaneous oxygen.

c: adjusted for age, sex, new onset atrial fibrillation, heart rate, systolic blood pressure, diastolic blood pressure, respiratory rate, saturation of percutaneous oxygen, congestive heart failure, hypertension, diabetes, chronic kidney disease, chronic liver disease, metastatic cancer, intubation, continuous kidney replacement therapy, blood culture positive, heart surgery, aorta surgery, glasgow coma scale.

d: adjusted for age, sex, new onset atrial fibrillation, heart rate, systolic blood pressure, diastolic blood pressure, respiratory rate, saturation of percutaneous oxygen, congestive heart failure, hypertension, diabetes, chronic kidney disease, chronic liver disease, metastatic cancer, intubation, continuous kidney replacement therapy, blood culture positive, heart surgery, aorta surgery, glasgow coma scale, norepinephrine, dopamine, dobutamine, epinephrine, vasopressin, rhythm control, rate control.