Fig. 7.

Effect of anti-IL-6 antibody on IL-6 levels 12 hours after CLP. Mice were subjected to CLP, given monoclonal anti-IL-6 or control IgG at 6 hours and had their blood drawn at 12 hours. Anti-IL-6 antibody markedly reduces IL-6 levels. Of note, this is the only experiment in the manuscript where IL-6 levels were not drawn at 6 hours and the only experiment where IL-6 levels were drawn after an intervention.