Table 2.
Measures of Knowledge, Risk Perception, Intent to Test, and Anxiety for Women at Low Risk of Carrying a BRCA1/2 Mutation*
|
Counselor Group (n = 61) |
Computer Group (n = 56) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Measures† | Before Counseling | After Counseling | Change | PValue‡ | Before Computer Use | After Computer Use | Change | PValue§ | After Computer Use and Counseling | PValue|| | PValue, Counselor vs Computer Group¶ |
| Knowledge, % correct responses | 50 | 80 | 29 | <.001 | 53 | 91 | 38 | <.001 | . . .# | . . .# | .03 |
| Relative risk perception, % | 90 | 78 | −12 | .05 | 82 | 83 | 1 | >.99 | 83 | >.99 | .18 |
| Absolute risk perception, mean (range) | 58 (0–100) | 42 (0–100) | −16 | <.001 | 59 (10–100) | 51 (10–90) | −8 | .001 | 42 (10–90) | <.001 | .02 |
| Genetic risk perception, % | 46 | 7 | −39 | <.001 | 41 | 34 | −7 | .16 | 11 | <.001 | .002 |
| Intent to test, % | 80 | 36 | −44 | <.001 | 82 | 67 | −15 | .05 | 42 | <.001 | .07 |
| State anxiety, mean (range) | 34 (20–72) | 30 (20–61) | −3 | .007 | 33 (20–52) | 33 (20–48) | 0 | .90 | 29 (20–47) | <.001 | .04 |
Low risk was defined as less than 10% chance of carrying a mutation.
Data for the measures are based on the following: relative risk perception: % indicating “much higher” or “a little higher” for the item, “Compared with other women your age, what are your chances of developing breast cancer in the future?”; absolute risk perception: mean response values (range) for the item, “What do you think your chances of getting breast cancer are on a scale from 0 to 100?”; genetic risk perception: % indicating “very likely” or “definitely” for the item, “In your opinion, how likely is it that you have an inherited gene mutation for breast cancer susceptibility?”; intent to test: % indicating “probably” or “definitely” will get tested for the item, “Present thoughts about having genetic testing for suceptibility to breast cancer”; and state anxiety: mean scores (range) on a scale from 20 to 80.
P values are for difference in outcomes between baseline and after counseling among counselor group.
P values are for difference in outcomes between baseline and after computer among computer group.
P values are for difference in outcomes between baseline and after counseling among computer group.
P values are for difference in change scores between counselor group and computer group.
Ellipses indicate data not applicable.