Table 3.
Measures of Knowledge, Risk Perception, Intent to Test and Anxiety for Women at High Risk for Carrying a BRCA1/2 Mutation*
|
Counselor Group (n = 44) |
Computer Group (n = 50) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Measures† | Before Counseling | After Counseling | Change | PValue‡ | Before Computer Use | After Computer Use | Change | PValue§ | After Computer Use and Counseling | PValue|| | PValue, Counselor vs Computer Group¶ |
| Knowledge, % correct responses | 58 | 86 | 29 | <.001 | 56 | 90 | 34 | <.001 | . . .# | . . .# | .22 |
| Relative risk perception, % | 83 | 86 | 3 | .65 | 85 | 84 | −1 | >.99 | 86 | .74 | .70 |
| Absolute risk perception, mean (range) | 62 (0–100) | 54 (10–90) | −8 | .002 | 67 (10–100) | 59 (10–100) | −9 | .03 | 56 (10–90) | .006 | .85 |
| Genetic risk perception, % | 68 | 56 | −12 | .17 | 67 | 58 | −9 | .10 | 61 | .48 | .80 |
| Intent to test, % | 89 | 95 | 7 | .08 | 96 | 89 | −6 | .32 | 85 | .18 | .13 |
| State anxiety, mean (range) | 38 (20–72) | 33 (20–75) | −5 | .001 | 33 (20–60) | 31 (20–52) | −2 | .08 | 30 (20–53) | .02 | .04 |
High risk was defined as 10% or higher chance of carrying a mutation.
Data for the measures are based on the following: relative risk perception: % indicating “much higher” or “a little higher” for the item, “Compared with other women your age, what are your chances of developing breast cancer in the future?”; absolute risk perception: mean response values (range) for the item, “What do you think your chances of getting breast cancer are on a scale from 0 to 100?”; genetic risk perception: % indicating “very likely” or “definitely” for the item, “In your opinion, how likely is it that you have an inherited gene mutation for breast cancer susceptibility?”; intent to test: % indicating “probably” or “definitely” will get tested for the item, “Present thoughts about having genetic testing for suceptibility to breast cancer”; and state anxiety: mean scores (range) on a scale from 20 to 80.
P values are for difference in outcomes between baseline and after counseling among counselor group.
P values are for difference in outcomes between baseline and after computer among computer group.
P values are for difference in outcomes between baseline and after counseling among computer group.
P values are for difference in change scores between counselor group and computer group.
Ellipses indicate data not available.