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. 2025 Aug 21;17(8):e90705. doi: 10.7759/cureus.90705

Table 2. Performance metrics at various neutrophil-to-lymphocyte ratio (NLR) cutoff values for predicting advanced stage (stages III and IV) breast cancer.

Baseline NLR cutoff 2.5 cut off value 3.0 cut off value 3.5 cut off value
True positive (TP) 19 7 12
True negative (TN) 4 28 12
False positive (FP) 31 7 23
False negative (FN) 2 14 9
Sensitivity 90.5% 33.3% 57.1%
Specificity 11.4% 80.0% 34.3%
Accuracy 41.1% 62.5% 42.9%
PPV 38.0% 50.0% 34.3%
NPV 66.7% 66.7% 57.1%
Youden’s J index 0.019 0.133 -0.086