Fig. 2.

Detection of lig sequences in Leptospira species.
A. Southern blot analysis. Genomic DNA from L. interrogans Fiocruz L1-130 (middle lane) and L. biflexa Patoc 1 (right lane) were digested with NsiI and PacI and probed in Southern blots with ligA, ligB and ligC specific probes.
B and C. PCR analysis. Leptospiral DNA was subjected to PCR analysis by degenerate primers designed to anneal to all lig genes in L. kirschneri RM52 and L. interrogans Fiocruz L1-130. The expected size of the PCR product is −0.5 kb.