Figure 2.

Complete gene sequence of TbPDE2B. Boxed amino acid regions indicate the two GAF domains and the catalytic domain identified by pfam sequence similarity to known domains in other proteins (42). * indicates the stop codon. Underlined YHN and HDX₂HX₄N motifs indicate PDE catalytic domains (see text). Italicized text indicates noncoding regions. Note that nucleotides are numbered beginning with 1 at the start ATG.