Table 3.
The impact of placenta accreta on the risk of adverse perinatal outcomes in twin vs. singleton pregnancies*
| Variables | Twin pregnancy |
Singleton pregnancy |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
|
Placenta accreta
|
Non-placenta accreta
|
P-value
|
Univariate analysis
|
Multivariate analysis
|
Placenta accreta
|
Non-placenta accreta
|
P-value
|
Univariate analysis
|
Multivariate analysis
|
| Premature delivery |
60 (34.29) |
284 (24.25) |
0.005† |
1.63 (1.16, 2.29) |
1.77 (1.24, 2.52) |
88 (7.32) |
619 (4.31) |
<0.001† |
1.75 (1.39, 2.21) |
1.67 (1.32, 2.11) |
| Caesarean section |
153 (87.43) |
688 (58.75) |
<0.001† |
4.88 (3.08, 7.75) |
4.87 (23.00, 7.90) |
130 (10.82) |
1313 (9.14) |
0.045† |
2.98 (2.63, 3.39) |
2.67 (2.34, 3.04) |
| Pelvic inflammation |
50 (28.57) |
172 (14.69) |
<0.001† |
2.3 2(1.61, 3.35) |
2.12 (1.44, 3.12) |
143 (11.90) |
742 (5.17) |
<0.001† |
2.48 (2.05, 3.00) |
2.04 (1.68, 2.49) |
| Postpartum haemorrhage |
17 (9.71) |
31 (2.65) |
<0.001† |
3.96 (2.14, 7.32) |
3.73 (1.95, 7.13) |
77 (6.41) |
402 (2.80) |
<0.001† |
2.38 (1.85, 3.06) |
2.422 (1.87, 3.14) |
| Atonic postpartum haemorrhage |
12 (6.86) |
21 (1.79) |
<0.001† |
4.03 (1.95, 8.35) |
3.99 (1.85, 8.63) |
16 (1.33) |
195 (1.36) |
0.938 |
0.98 (0.59, 1.64) |
0.99 (0.58, 1.68) |
| Premature rupture of membranes |
20 (11.43) |
117 (9.99) |
0.558 |
1.16 (0.70, 1.92) |
1.12 (0.66, 1.89) |
45 (3.74) |
328 (2.28) |
0.001† |
1.66 (1.21, 2.29) |
1.64 (1.19, 2.26) |
| Uterine rupture |
3 (1.71) |
2 (0.17) |
0.002† |
10.20 (1.69, 61.45) |
26.42 (2.28, 306.63) |
26 (2.16) |
104 (0.72) |
<0.001† |
3.03 (1.96, 4.68) |
2.78 (1.78, 4.32) |
| Umbilical entanglement |
36 (20.57) |
207 (17.68) |
0.353 |
1.21 (0.81, 1.79) |
1.14 (0.75, 1.71) |
308 (25.62) |
3822 (26.62) |
0.454 |
0.95 (0.83, 1.09) |
0.97 (0.85, 1.11) |
| Foetal distress | 6 (3.43) | 26 (2.22) | 0.328 | 1.56 (0.63, 3.85) | 1.80 (0.70, 4.62) | 130 (10.82) | 1313 (9.14) | 0.055 | 1.21 (0.99, 1.458) | 1.34 (1.10, 1.63) |
ART – assisted reproductive technology, GDM – gestational diabetes mellitus, FGR – foetal growth restriction, ICP – intrahepatic cholestasis of pregnancy, PBMI – pre-pregnancy body mass index, PE – preeclampsia
*aOR adjusted for maternal age, PBMI, nulliparity, primigravida, history of caesarean section, history of alcoholism, racquet placenta, velaria placenta, placenta previa, GDM, PE, ICP, FGR, ART.
†P < 0.05.