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(a) Two aromatic residues (shown in ball-and-stick representation) interacting with high value of interaction strength (Iij=8%). The non-covalent atom–atom contacts occuring within a distance of 0.45 nm (4.5 Å) are indicated by thin lines. (b) Hubs: a phenylalanine residue (shown in van der Waals representation) interacting with seven other residues (shown in ball-and-stide representation), thus acting as a hub in the protein structure.
