Table 1. Alkalinization rate constants (s⁻¹) of transfected HEK-293 and MDCK cells.

* P<0.001 compared with WT; † P<0.001 compared with RhBG; ‡ P<0.02 compared with RhBG; nd, not determined; n values in parentheses.

	Rate constant (s−1)
	HEK-293				MDCK
Substrate	WT	RhBG	RhCG	RhAG	WT	RhBG	RhCG
NH4+	0.18±0.011 (6)	1±0.15* (5)	0.88±0.07* (5)	0.15±0.04 (3)	0.18±0.009 (4)	0.76±0.007* (4)	0.45±0.02* (4)
CH3NH3+	0.029±0.01 (6)	0.53±0.06* (4)	0.11±0.023‡ (3)	0.04±0.01 (3)	0.042±0.02 (4)	0.35±0.01* (4)	0.045±0.012† (4)
C2H5NH3+	0.041 (2)	0.11 (2)	0.043 (2)	nd	nd	nd	nd