Figure 6. Inhibition of binding of vWF to collagen I by A/C-e using the BIAcore™ 3000 system.

(A) vWF at different concentrations was injected over immobilized collagen I. (B) vWF at different concentrations and saturated with A/C-e (450 nM) was injected over immobilized collagen I saturated with A/C-e (450 nM). The injection flow rate was 50 μl/min. The arrows indicate the beginning and the end of injections. RU, response units.