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. 2005 Sep 26;391(Pt 1):69–76. doi: 10.1042/BJ20050483

Table 1. Kinetic evaluation of the interaction of venom proteins with collagen I immobilized on CM-5 sensor chip in the BIAcore™ 3000 system.

Evaluation was performed according to a 1:1 binding model. Results are the means±S.D. for six different analyte concentrations. n.d., not determined.

Kd (μM) kd (×10−3 s−1) ka (×103 M−1·s−1)
Jararhagin 0.0216 1.22±0.0084 56.4±1.3
Atrolysin A 0.117 4.71±0.0374 40.2±3.77
Catrocollastatin C 0.777 4.23±0.0258 5.45±0.105
A/C-e 0.0726 1.93±0.014 26.5±0.271
Atrolysin C (Ht-C) 509 n.d. n.d.