Table 7. Substrate specificities of human, mouse and porcine Gal3ST-2 enzymes.
The concentrations of the substrates were 1 mM. The enzymatic activities represent the means for four independent experiments (S.D. was <5%). The relative values were calculated with respect to the value of core 1, which was set as 100.
| Core1 | Core1-O-pNP | Core1-O-Bn | Type 1 | Type 2 | Core2-O-pNP | Lactose | LNT | MonoGP | BiGP | |
|---|---|---|---|---|---|---|---|---|---|---|
| Human Gal3ST-2 | 100 | 121 | 120 | 55 | 108 | 70 | 114 | 71 | 99 | 80 |
| Mouse Gal3ST-2 | 100 | 123 | 85 | 15 | 102 | 37 | 60 | 39 | 49 | 52 |
| Porcine Gal3ST-2 | 100 | 85 | 124 | 39 | 15 | 27 | 11 | 69 | 19 | 17 |