Table 3.
Summary of CMV viral load kinetics by episode.
| CMV episode | 1 Episode | 2+ Episodes | Total | P-value |
|---|---|---|---|---|
| Duration of episode, mean (SD) | 18.2 (10.8) | 23.4 (20.3) | 19.0 (12.9) | 0.2548 |
| CMV viremia only | 15.8 (7.2) | 13.6 (6.2) | 15.4 (7.1) | 0.196 |
| CMV viremia with clinical complications | 18.6 (10.9) | 26.1 (23.5) | 19.6 (13.7) | 0.150 |
| CMV viremia with clinical complications and hospitalization | 23.5 (18.4) | 33.1 (9.7) | 25.9 (17.0) | 0.056 |
| Maximum viral load (log10), mean (SD) | 4.0 (0.7) | 3.8 (0.6) | 4.0 (0.7) | 0.0721 |
| CMV viremia only | 8.5 (1.2) | 8.2 (1.4) | 8.4 (1.2) | 0.161 |
| CMV viremia with clinical complications | 9.3 (1.7) | 8.7 (1.2) | 9.2 (1.7) | 0.061 |
| CMV viremia with clinical complications and hospitalization | 10.6 (2.3) | 10.3 (0.8) | 10.5 (2.0) | 0.577 |
| AUC (log10 IU/mL*days), mean (SD) | 73.8 (53.2) | 89.8 (81.1) | 76.4 (58.8) | 0.5481 |
| CMV viremia only | 57.4 (29.5) | 47.9 (23.4) | 55.6 (28.6) | 0.1629 |
| CMV viremia with clinical complications | 76.4 (54.6) | 99.4 (92.1) | 79.7 (61.8) | 0.3862 |
| CMV viremia with clinical complications and hospitalization | 107.5 (84.4) | 147.2 (44.9) | 117.4 (77.7) | 0.0824 |
AUC, area under the curve; CMV, cytomegalovirus; SD, standard deviation.