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. Author manuscript; available in PMC: 2025 Aug 25.
Published in final edited form as: Ann Surg Oncol. 2025 Jul 19;32(13):9767–9775. doi: 10.1245/s10434-025-17906-5

Table 2.

Adjusted logistic regression model of factors associated with nodal pathologic complete response among patients with clinically node positive breast cancer after neoadjuvant chemotherapy

ORa 95% CIb p-value

Age 0.99 [0.99 – 0.99] <0.001

Race (ref: white)
 Black 0.90 [0.85 – 0.95] <0.001
 Other 1.16 [0.82 – 1.65] 0.41

Place of residence (ref: metro/urban)
 Rural 1.11 [0.92 – 1.34] 0.29

Insurance status (ref: not insured)
 Insured 1.03 [0.90 – 1.18] 0.68

Facility type (ref: academic/research)
 Community Programs 0.91 [0.86 – 0.96] <0.001
 Integrated Network Cancer Program 0.97 [0.91 – 1.03] 0.30

CCIc (ref: 0)
 1 0.96 [0.89 – 1.03] 0.22
 >1 0.85 [0.74 – 0.96] 0.012

Subtype of breast cancer (ref: TNBCc)
 ER+/HER2+ 0.91 [0.81 – 1.01] 0.08
 ER+/HER2− 0.41 [0.38 – 0.44] <0.001
 ER−/HER2+ 1.32 [1.21 – 1.44] <0.001

Endocrine therapy (ref: no)
 Yes 0.74 [0.68 – 0.81] <0.001

Immunotherapy (ref: no)
 Yes 1.60 [1.46 – 1.74] <0.001

cT (ref: cT0)
 1 1.09 [0.72 – 1.64] 0.70
 2 1.05 [0.69 – 1.58] 0.83
 3 0.90 [0.59 – 1.36] 0.62
 4 0.78 [0.52 – 1.18] 0.24

cN (ref: cN1)
 2 0.76 [0.71 – 0.82] <0.001
 3 0.79 [0.73 – 0.87] <0.001

Histology (ref: ductal)
 Lobular 0.62 [0.54 – 0.73] <0.001
 Other 0.75 [0.69 – 0.82] <0.001

Grade (ref: 1)
 2 1.45 [1.21 – 1.72] <0.001
 3 2.32 [1.95 – 2.76] <0.001
a

Odds ratio

b

Confidence interval

c

Triple negative breast cancer