Table 2.
Adjusted logistic regression model of factors associated with nodal pathologic complete response among patients with clinically node positive breast cancer after neoadjuvant chemotherapy
| ORa | 95% CIb | p-value | |
|---|---|---|---|
|
| |||
| Age | 0.99 | [0.99 – 0.99] | <0.001 |
|
| |||
| Race (ref: white) | |||
| Black | 0.90 | [0.85 – 0.95] | <0.001 |
| Other | 1.16 | [0.82 – 1.65] | 0.41 |
|
| |||
| Place of residence (ref: metro/urban) | |||
| Rural | 1.11 | [0.92 – 1.34] | 0.29 |
|
| |||
| Insurance status (ref: not insured) | |||
| Insured | 1.03 | [0.90 – 1.18] | 0.68 |
|
| |||
| Facility type (ref: academic/research) | |||
| Community Programs | 0.91 | [0.86 – 0.96] | <0.001 |
| Integrated Network Cancer Program | 0.97 | [0.91 – 1.03] | 0.30 |
|
| |||
| CCIc (ref: 0) | |||
| 1 | 0.96 | [0.89 – 1.03] | 0.22 |
| >1 | 0.85 | [0.74 – 0.96] | 0.012 |
|
| |||
| Subtype of breast cancer (ref: TNBCc) | |||
| ER+/HER2+ | 0.91 | [0.81 – 1.01] | 0.08 |
| ER+/HER2− | 0.41 | [0.38 – 0.44] | <0.001 |
| ER−/HER2+ | 1.32 | [1.21 – 1.44] | <0.001 |
|
| |||
| Endocrine therapy (ref: no) | |||
| Yes | 0.74 | [0.68 – 0.81] | <0.001 |
|
| |||
| Immunotherapy (ref: no) | |||
| Yes | 1.60 | [1.46 – 1.74] | <0.001 |
|
| |||
| cT (ref: cT0) | |||
| 1 | 1.09 | [0.72 – 1.64] | 0.70 |
| 2 | 1.05 | [0.69 – 1.58] | 0.83 |
| 3 | 0.90 | [0.59 – 1.36] | 0.62 |
| 4 | 0.78 | [0.52 – 1.18] | 0.24 |
|
| |||
| cN (ref: cN1) | |||
| 2 | 0.76 | [0.71 – 0.82] | <0.001 |
| 3 | 0.79 | [0.73 – 0.87] | <0.001 |
|
| |||
| Histology (ref: ductal) | |||
| Lobular | 0.62 | [0.54 – 0.73] | <0.001 |
| Other | 0.75 | [0.69 – 0.82] | <0.001 |
|
| |||
| Grade (ref: 1) | |||
| 2 | 1.45 | [1.21 – 1.72] | <0.001 |
| 3 | 2.32 | [1.95 – 2.76] | <0.001 |
Odds ratio
Confidence interval
Triple negative breast cancer