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. 2025 Jul 8;5(4):706–725. doi: 10.1021/acsbiomedchemau.5c00084

2. MIC Values in μmol/L as a Function of poly-R/poly-K Motif Size for Natural Peptide Sequences for E. coli .

  position of (n) consecutive arginine/lysine amino acids (E. coli)
  START
MIDDLE
END
motif size (n) R K R K R K
R/K 16.31 ± 1.68 (157)** 18.73 ± 1.08 (460)** 16.62 ± 1.63 (149)* 21.73 ± 0.97 (623)* 16.52 ± 1.40 (245)* 23.33 ± 1.01 (643)*
RR/KK 15.33 ± 4.73 (16) 10.13 ± 3.35 (35) 15.55 ± 4.98 (17)* 28.31 ± 2.83 (92)* 7.88 ± 2.85 (25)* 23.06 ± 2.07 (132)*
RRR/KKK n.a. 1.00 ± 0.00 (2) 10.48 ± 4.68 (3) n.a. 1.86 ± 0.77 (6)** 5.28 ± 2.28 (6)**
a

For more details, see Table footnote.