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. 2025 Jun 4;5(4):553–564. doi: 10.1021/acsbiomedchemau.4c00130

3. Properties of Doxorubicin Combined with BQACs.

Compound IC50 (μM) IC50 of doxorubicin in combination (DOX/BQAC 1:40) (μM) Combination index
Doxorubicin 0.066 ± 0.006    
8a 2.2 0.035 ± 0.004 1.15
9a 5.0 0.042 ± 0.007 0.97
11a 2.0 0.027 ± 0.006 0.95
26 6.6 0.0630 ± 0.0008 1.33
31 1.8 0.030 ± 0.005 1.13