Table 6.

Adverse events per patient group.

	Standard dosing	Model-based dosing
Warfarin-related	n = 5 patients	n = 2 patients
Hemorrhagic, gastrointestinal bleed	1	2
Hemorrhagic, hematuria	1	0
Hemorrhagic, epistaxis	2	0
Thromboembolic, deep venous thrombosis	1	0
Thromboembolic, pulmonary embolism	1	0
Warfarin-unrelated	n = 3 patients	n = 3 patients
Back pain	0	1
Dizziness	2	0
Hyperglycemia	1	0
Incision infection	0	1
Rash (trunk)	0	1
Tympanic membrane perforation	1	0
Urinary tract infection	0	1
Vaginal yeast infection	0	1
Bridging therapy
Subcutaneous low molecular weight heparin	0	0
Intravenous heparin	0	0
Reversal of anticoagulation
Subcutaneous vitamin K	2	0
Intravenous fresh frozen plasma	0	0