. 2005 Aug;3(3):166–175. doi: 10.3121/cmr.3.3.166

Table 1.

Multiple subsets of murine splenic dendritic cells perform specialized functions.²⁰

Dendritic cell subset	Markers	Function
Myeloid	CD11c⁺CD205⁻CD11b⁺ CD8α ⁻CD4^+/−	Located in splenic marginal zones. Efficient stimulation of CD4⁺ and CD8⁺ T cells. Favor Th2 differentiation during inflammatory conditions.
Lymphoid	CD11c⁺CD205⁺CD11b⁻ CD8α ⁺CD4⁻	Efficiently cross-present exogenous antigens to CD8⁺ CTL. Favor Th1 differentiation during inflammatory conditions. Maintain cross-tolerance to self antigens.
Plasmacytoid	CD11c⁺CD11b⁻B220⁺ GR1^+/−	Possibly contribute to peripheral self-tolerance. Mediate anti-viral responses through production of IFN-α .