Table 2.
Sensitivity and specificity of specific antinuclear antibody tests.1
| Antigen | Associated Condition | Sensitivity (%) | Specificity (%) |
| Anticentromere | Limited cutaneous systemic sclerosis | 65 | 99.9 |
| Anti-dsDNA antibody | Systemic lupus erythematosus | 57 | 97 |
| Anti-SSB/La antibody | Sjögren’s, subacute cutaneous lupus erythematosus, neonatal lupus syndrome | 16–40 | 94 |
| Anti-SSA/Ro antibody | Sjögren’s, subacute cutaneous lupus erythematosus, neonatal lupus syndrome | 8–70 | 87 |
| Anti-Smooth muscle antibody | Systemic lupus erythematosus | 25–30 | High* |
| Anti-U3-RNP antibody | Scleroderma | 12 | 96 |
| Scl-70 | Systemic sclerosis | 20 | 100 |
* Precise data not available.