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. 2025 Aug 7;13:a26636372. doi: 10.1055/a-2663-6372

Table 3 Independent predictors of hypoxia on multivariable and univariable regression analysis in full analysis set.

Variables Univariable model Multivariable model
OR (95%CI) P value OR (95%CI) P value
ASA, American Society of Anesthesiologists; BMI, body mass index; CI, confidence interval; OR, odds ratio; SpO 2 , pulse oxygen saturation.
Sex
Male 1 (ref) 1 (ref)
Female 1.37 (1.07–1.76) 0.013 1.65 (1.25–2.18) < 0.001
Age 1.03 (0.99–1.06) 0.16 1.04 (1.00–1.08) 0.050
BMI (kg/m 2 ) 1.14 (1.10–1.19) < 0.001 1.12 (1.07–1.17) < 0.001
ASA physical status
1 1 (ref) 1 (ref)
2 0.91 (0.62–1.34) 0.628 0.79 (0.51–1.22) 0.286
Procedure type
Gastroscopy 1 (ref) 1 (ref)
Colonoscopy 0.42 (0.27–0.67) < 0.001 0.38 (0.24–0.61) < 0.001
Gastrointestinal Endoscopy 1.41 (1.06–1.88) 0.019 1.41 (0.98–2.01) 0.063
Initial propofol (mg) 1.02 (1.01–1.02) < 0.001 1.02 (1.01–1.02) < 0.001
Mallampati classification
1 1 (ref) 1 (ref)
2 1.52 (1.13–2.03) 0.005 1.21 (0.88–1.67) 0.241
3 1.78 (1.26–2.51) 0.001 1.38 (0.93–2.05) 0.111
4 1.88 (0.93–3.80) 0.081 1.30 (0.59–2.89) 0.515
Snore
No 1 (ref) 1 (ref)
Yes 1.84 (1.44–2.37) < 0.001 1.51 (1.13–2.02) 0.005
Pre-anesthesia SpO 2 (%) 0.73 (0.67–0.80) < 0.001 0.73 (0.66–0.81) < 0.001