Skip to main content
. 2025 Jun 23;16(16):3138–3148. doi: 10.1021/acschemneuro.5c00165

2. Biological Activity of the Synthesized Compounds with Serial Numbers 34–147 Was Assessed in Mouse Tail Suspension and Forced Swimming Experiments with Paroxetine as the Control Group.

sample name tail suspension experiment (immobilization time in seconds) forced swimming experiment (immobilization time in seconds)
solvent control group 95.4(±38.8) 123.6(±52.3)
sertraline 48.3(±18.2) 58.7(±42.7)
2 41.1(±13.4) 49.4(±13.5)
3 40.7(±11.7) 47.4(±15.2)
4 37.1(±12.3) 43.6(±20.6)
5 39.2(±13.0) 46.0(±32.2)
9 37.4(±15.2) 51.1(±34.5)
13 37.2(±15.8) 51.4(±34.5)
19 39.2(±7.8) 50.5(±20.4)
20 37.6(±12.3) 44.1(±30.8)
30 40.1(±13.4) 48.1(±33.0)
31 36.5(±12.5) 43.4(±30.2)
39 40.6(±13.3) 49.1(±33.4)
53 35.0(±12.1) 41.1(±28.2)
54 39.5(±13.2) 46.4(±22.2)
55 38.0(±7.0) 49.1(±26.2)
57 36.0(±12.1) 42.5(±30.0)
59 41.6(±14.2) 48.1(±24.4)
67 38.0(±12.5) 44.5(±21.1)
76 39.2(±9.1) 49.4(±17.2)
77 38.4(±13.1) 45.4(±21.6)
78 39.3(±8.0) 50.7(±22.1)
81 35.4(±12.1) 42.0(±29.2)
93 40.0(±10.8) 50.1(±11.1)
97 40.4(±10.4) 50.1(±10.2)
101 39.7(±13.3) 47.4(±22.4)