2. Biological Activity of the Synthesized Compounds with Serial Numbers 34–147 Was Assessed in Mouse Tail Suspension and Forced Swimming Experiments with Paroxetine as the Control Group.
| sample name | tail suspension experiment (immobilization time in seconds) | forced swimming experiment (immobilization time in seconds) |
|---|---|---|
| solvent control group | 95.4(±38.8) | 123.6(±52.3) |
| sertraline | 48.3(±18.2) | 58.7(±42.7) |
| 2 | 41.1(±13.4) | 49.4(±13.5) |
| 3 | 40.7(±11.7) | 47.4(±15.2) |
| 4 | 37.1(±12.3) | 43.6(±20.6) |
| 5 | 39.2(±13.0) | 46.0(±32.2) |
| 9 | 37.4(±15.2) | 51.1(±34.5) |
| 13 | 37.2(±15.8) | 51.4(±34.5) |
| 19 | 39.2(±7.8) | 50.5(±20.4) |
| 20 | 37.6(±12.3) | 44.1(±30.8) |
| 30 | 40.1(±13.4) | 48.1(±33.0) |
| 31 | 36.5(±12.5) | 43.4(±30.2) |
| 39 | 40.6(±13.3) | 49.1(±33.4) |
| 53 | 35.0(±12.1) | 41.1(±28.2) |
| 54 | 39.5(±13.2) | 46.4(±22.2) |
| 55 | 38.0(±7.0) | 49.1(±26.2) |
| 57 | 36.0(±12.1) | 42.5(±30.0) |
| 59 | 41.6(±14.2) | 48.1(±24.4) |
| 67 | 38.0(±12.5) | 44.5(±21.1) |
| 76 | 39.2(±9.1) | 49.4(±17.2) |
| 77 | 38.4(±13.1) | 45.4(±21.6) |
| 78 | 39.3(±8.0) | 50.7(±22.1) |
| 81 | 35.4(±12.1) | 42.0(±29.2) |
| 93 | 40.0(±10.8) | 50.1(±11.1) |
| 97 | 40.4(±10.4) | 50.1(±10.2) |
| 101 | 39.7(±13.3) | 47.4(±22.4) |