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. 2025 Aug 10;147(33):29801–29814. doi: 10.1021/jacs.5c05736

2. DNA-Binding Constants (K b) and Binding-Site Size Determined for Enantiomers of 1 2+, Using the Bard-Fitting of Luminescence at 630 nm, for DNA-Titrated Systems in the Presence of 50 mM Potassium Phosphate Buffer at pH 7.

System Binding constant K b (M–1)/binding-site size
Δ-1 2+/st 2.4(±0.8) × 106/2.5(±0.1)
Λ-1 2+/st 2.2(±0.5) × 106/1.1(±0.1)
Δ-1 2+/d(G5C5)2 7.8(±0.8) × 105/2.1(±0.1)
Λ-1 2+/d(G5C5)2 1.3(±0.2) × 106/2.2(±0.1)
Δ-1 2+/htel 2.7(±0.2) × 105/2.7(±0.1)
Λ-1 2+/htel 5.7(±0.2) × 105/1.4(±0.1)