Extended Data Figure 4. Dual N- and C-terminal labeling of GS-MBP-TeCH using eSrtA and MccB/subtiligase.

(A) Scheme for dual N- and C-terminal label of GS-MBP-TeCH with MccB/subtiligase and eSrtA. The magenta circle represent azidoAla and the cyan circle represents 5-FAM. (B) Telescoping one-pot dual labeling of GS-MBP-TeCH with eSrtA and MccB/subtiligase. (C) Concurrent one-pot dual labeling of GS-MBP-TeCH with eSrtA and MccB/subtiligase.