Table 1.
The baseline characteristics of participants
| AIP group | Q1 (<-0.31) | Q2 (-0.31- -0.11) | Q3 (-0.11-0.10) | Q4 (≥ 0.10) | P-value |
|---|---|---|---|---|---|
| Participants | 31,980 | 31,988 | 31,983 | 31,985 | |
| Age (years) | 40.3 ± 10.7 | 42.7 ± 12.3 | 45.0 ± 12.9 | 46.6 ± 12.5 | < 0.001 |
| Gender, n (%) | < 0.001 | ||||
| Male | 8,761 (27.4) | 14,901 (46.6) | 19,810 (61.9) | 24,761 (77.4) | |
| Female | 23,219 (72.6) | 17,087 (53.4) | 12,173 (38.1) | 7,224 (22.6) | |
| Country, n (%) | < 0.001 | ||||
| Chinese | 24,616 (77.0) | 28,753 (89.9) | 29,376 (91.8) | 29,738 (93.0) | |
| Japanese | 7,364 (23.0) | 3,235 (10.1) | 2,607 (8.2) | 2,247 (7.0) | |
| Smoking status, n (%) | < 0.001 | ||||
| Non-smoker | 27,975 (87.5) | 26,048 (81.4) | 23,783 (74.4) | 20,781 (65.0) | |
| Smoker | 4,005 (12.5) | 5,940 (18.6) | 8,200 (25.6) | 11,204 (35.0) | |
| Drinking status, n (%) | < 0.001 | ||||
| Non-drinker | 24,756 (77.4) | 25,593 (80.0) | 24,780 (77.5) | 23,547 (73.6) | |
| Drinker | 7,224 (22.6) | 6,395 (20.0) | 7,203 (22.5) | 8,438 (26.4) | |
| BMI (kg/m²) | 21.1 ± 2.5 | 22.4 ± 2.9 | 23.7 ± 3.1 | 25.2 ± 3.0 | < 0.001 |
| SBP (mmHg) | 112.1 ± 14.5 | 116.7 ± 15.7 | 120.6 ± 16.3 | 124.4 ± 16.2 | < 0.001 |
| DBP (mmHg) | 69.6 ± 9.8 | 72.6 ± 10.3 | 75.1 ± 10.7 | 78.2 ± 10.9 | < 0.001 |
| FPG (mmol/L) | 4.8 ± 0.5 | 4.9 ± 0.5 | 4.9 ± 0.5 | 5.0 ± 0.6 | < 0.001 |
| TC (mmol/L) | 4.6 ± 0.8 | 4.7 ± 0.9 | 4.9 ± 0.9 | 5.1 ± 0.9 | < 0.001 |
| TG (mmol/L) | 0.6 (0.5–0.7) | 0.9 (0.8-1.0) | 1.3 (1.1–1.4) | 2.1 (1.7–2.7) | < 0.001 |
| HDL-C (mmol/L) | 1.6 ± 0.3 | 1.4 ± 0.2 | 1.3 ± 0.2 | 1.1 ± 0.2 | < 0.001 |
| LDL-C (mmol/L) | 2.6 ± 0.6 | 2.7 ± 0.7 | 2.9 ± 0.7 | 3.0 ± 0.8 | < 0.001 |
| ALT (U/L) | 14.0 (11.0-18.4) | 16.0 (12.0-22.4) | 19.0 (14.0-27.9) | 25.7 (18.0–38.0) | < 0.001 |
| AST (U/L) | 19.2 (15.6–24.0) | 20.9 (16.8–25.8) | 22.2 (18.0-27.9) | 24.8 (19.8–31.2) | < 0.001 |
| AIP | -0.5 ± 0.1 | -0.2 ± 0.1 | -0.0 ± 0.1 | 0.3 ± 0.2 | < 0.001 |
Values are n (%), mean ± SD or medians (quartiles)
BMI, body mass index; FPG, fasting plasma glucose; DBP, diastolic blood pressure; TC, total cholesterol; SBP, systolic blood pressure; TG, triglyceride; ALT, alanine aminotransferase; LDL-c, low-density lipid cholesterol; AST, aspartate aminotransferase; HDL-c, high-density lipoprotein cholesterol; AIP, atherogenic index of plasma