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. 2025 Aug 22;17:349. doi: 10.1186/s13098-025-01907-1

Table 4.

Relationship between AIP and the incident diabetes in different models

AIP Exposure Overall (HR,95%CI, P) Chinese (HR,95%CI, P) Japanese (HR,95%CI, P)
Model I:
AIP 8.472 (7.426, 9.666) P < 0.001 6.771 (5.814, 7.886) P < 0.001 10.260 (7.713, 13.648) P < 0.001
AIP Quartiles
Q1 Ref. Ref. Ref.
Q2 2.064 (1.693, 2.516) P < 0.001 1.839 (1.444, 2.342) P < 0.001 1.835 (1.279, 2.634) P = 0.001
Q3 4.097 (3.424, 4.902) P < 0.001 3.540 (2.837, 4.418) P < 0.001 3.629 (2.628, 5.012) P < 0.001
Q4 7.592 (6.411, 8.989) P < 0.001 6.199 (5.021, 7.653) P < 0.001 7.525 (5.617, 10.080) P < 0.001
P for trend P < 0.001 P < 0.001 P < 0.001
Model II:
AIP 3.032 (2.582, 3.560) P < 0.001 2.499 (2.081, 3.002) P < 0.001 4.119 (2.892, 5.866) P < 0.001
AIP Quartiles
Q1 Ref. Ref. Ref.
Q2 1.266 (1.036, 1.548) P = 0.021 1.180 (0.925, 1.507) P = 0.183 1.142 (0.787, 1.657) P = 0.485
Q3 1.768 (1.465, 2.133) P < 0.001 1.567 (1.248, 1.969) P < 0.001 1.743 (1.229, 2.474) P = 0.002
Q4 2.445 (2.033, 2.939) P < 0.001 2.046 (1.636, 2.559) P < 0.001 2.838 (2.020, 3.987) P < 0.001
P for trend P < 0.001 P < 0.001 P < 0.001
Model III:
AIP 2.390 (2.047, 2.792) P < 0.001 1.843 (1.540, 2.206) P < 0.001 2.420 (1.665, 3.516) P < 0.001
AIP Quartiles
Q1 Ref. Ref. Ref.
Q2 1.204 (0.984, 1.473) P = 0.071 1.099 (0.861, 1.403) P = 0.449 0.893 (0.612, 1.303) P = 0.557
Q3 1.718 (1.423, 2.074) P < 0.001 1.432 (1.140, 1.800) P = 0.002 1.346 (0.944, 1.920) P = 0.101
Q4 2.197 (1.825, 2.643) P < 0.001 1.704 (1.360, 2.134) P < 0.001 1.771 (1.237, 2.536) P = 0.002
P for trend P < 0.001 P < 0.001 P < 0.001

Model I: We did not adjust other covariates

Model II: We adjust age, gender, BMI, SBP, DBP, smoking, and drinking status

Model III: We adjust age, gender, BMI, SBP, DBP, FPG, LDL-c, ALT, AST, smoking, and drinking status

HR, Hazard ratios; CI: confidence, Ref: reference; AIP, atherogenic index of plasma