Table 4.
Relationship between AIP and the incident diabetes in different models
AIP Exposure | Overall (HR,95%CI, P) | Chinese (HR,95%CI, P) | Japanese (HR,95%CI, P) |
---|---|---|---|
Model I: | |||
AIP | 8.472 (7.426, 9.666) P < 0.001 | 6.771 (5.814, 7.886) P < 0.001 | 10.260 (7.713, 13.648) P < 0.001 |
AIP Quartiles | |||
Q1 | Ref. | Ref. | Ref. |
Q2 | 2.064 (1.693, 2.516) P < 0.001 | 1.839 (1.444, 2.342) P < 0.001 | 1.835 (1.279, 2.634) P = 0.001 |
Q3 | 4.097 (3.424, 4.902) P < 0.001 | 3.540 (2.837, 4.418) P < 0.001 | 3.629 (2.628, 5.012) P < 0.001 |
Q4 | 7.592 (6.411, 8.989) P < 0.001 | 6.199 (5.021, 7.653) P < 0.001 | 7.525 (5.617, 10.080) P < 0.001 |
P for trend | P < 0.001 | P < 0.001 | P < 0.001 |
Model II: | |||
AIP | 3.032 (2.582, 3.560) P < 0.001 | 2.499 (2.081, 3.002) P < 0.001 | 4.119 (2.892, 5.866) P < 0.001 |
AIP Quartiles | |||
Q1 | Ref. | Ref. | Ref. |
Q2 | 1.266 (1.036, 1.548) P = 0.021 | 1.180 (0.925, 1.507) P = 0.183 | 1.142 (0.787, 1.657) P = 0.485 |
Q3 | 1.768 (1.465, 2.133) P < 0.001 | 1.567 (1.248, 1.969) P < 0.001 | 1.743 (1.229, 2.474) P = 0.002 |
Q4 | 2.445 (2.033, 2.939) P < 0.001 | 2.046 (1.636, 2.559) P < 0.001 | 2.838 (2.020, 3.987) P < 0.001 |
P for trend | P < 0.001 | P < 0.001 | P < 0.001 |
Model III: | |||
AIP | 2.390 (2.047, 2.792) P < 0.001 | 1.843 (1.540, 2.206) P < 0.001 | 2.420 (1.665, 3.516) P < 0.001 |
AIP Quartiles | |||
Q1 | Ref. | Ref. | Ref. |
Q2 | 1.204 (0.984, 1.473) P = 0.071 | 1.099 (0.861, 1.403) P = 0.449 | 0.893 (0.612, 1.303) P = 0.557 |
Q3 | 1.718 (1.423, 2.074) P < 0.001 | 1.432 (1.140, 1.800) P = 0.002 | 1.346 (0.944, 1.920) P = 0.101 |
Q4 | 2.197 (1.825, 2.643) P < 0.001 | 1.704 (1.360, 2.134) P < 0.001 | 1.771 (1.237, 2.536) P = 0.002 |
P for trend | P < 0.001 | P < 0.001 | P < 0.001 |
Model I: We did not adjust other covariates
Model II: We adjust age, gender, BMI, SBP, DBP, smoking, and drinking status
Model III: We adjust age, gender, BMI, SBP, DBP, FPG, LDL-c, ALT, AST, smoking, and drinking status
HR, Hazard ratios; CI: confidence, Ref: reference; AIP, atherogenic index of plasma