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. 2025 Aug 22;17:350. doi: 10.1186/s13098-025-01883-6

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© The Author(s) 2025

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 3 — Summary results of the MR analysis between OAB and Mets. OAB, overactive bladder; Mets, metabolic syndrome; T2DM, type 2 diabetes mellitus; BMI, body mass index; WC, waist circumference; FBG, fasting blood glucose; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; BCCO, bladder: calcified/ contracted/ overactive; UFI, urinary frequency/ Incontinence; nSNP, number of instrumental SNPs selected; OR, odd ratio; p_val, p value for the MR analysis; p_adj, Benjamini-Hochberg False discovery rate adjusted p value; Het_p, p value of the test of heterogeneity of instrumental SNP; MR_Egger, p value of MR-Egger intercept test; MR_PRESSO, p value of MR-PRESSO global horizontal pleiotropy test