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. 2025 Aug 21;16:15. doi: 10.1186/s13326-025-00337-2

Table 3.

MedDRA concepts mapped from the combination of SEND concepts for organ Liver and finding Necrosis. A penalty score of 0 denotes exact mapping, other scores are inexact. Negative scores indicate that the mapping disregarded the organ

MedDRA concept Penalty score
Hepatic necrosis 0
Liver injury 1
Zieve syndrome 1
Hepatic cytolysis 1
Cirrhosis alcoholic 1
Hepatitis alcoholic 1
Fatty liver alcoholic 1
Hepatocellular injury 1
Alcoholic liver disease 1
Acute yellow liver atrophy 1
Hepatocellular damage neonatal 1
Traumatic liver injury 1
Hepatic lesion 2
Hepatic infarction 2.1
Necrosis -1
Gangrene -2
Infarction -2
Necrobiosis -2
Fat necrosis -2
Septic necrosis -2
Tumour necrosis -2
Necrosis ischaemic -2
Osteonecrosis -2.1
Tissue injury -2.1
Skin exfoliation -2.1