Table 4.
Number of mappings from preclinical to clinical concepts and vice versa. The source for the mappings is based on all unique combinations of HPATH/MA and SEND terms in the preclinical databases and all MedDRA preferred terms. If multiple mappings for a source concept are available, only one mapping with the best (lowest) penalty score is counted. Penalty scores are rounded. Mappings with absolute penalty scores of three or more are combined with the missing mappings under inf. Negative penalties indicate that the organ is not mapped
| Mapping | Best Mapping Score | Number | ||||||
|---|---|---|---|---|---|---|---|---|
| Source | Target | 0 (%) | 1 (%) | 2 (%) | -1 (%) | -2 (%) | Inf (%) | N |
| HPATH/MA | MedDRA | 686 (8) | 1,333 (16) | 1,125 (14) |
629 (8) |
2,053 (25) |
2,383 (29) |
8,209 |
| MedDRA | HPATH/MA | 2,856 (11) | 2,356 (9) | 1,101 (4) | 2,355 (9) | 1,039 (4) | 15,726 (62) | 25,433 |
| SEND | MedDRA | 428 (13) |
677 (20) |
653 (19) |
717 (21) |
372 (11) |
505 (15) |
3,352 |
| MedDRA | SEND | 2,697 (11) | 2,388 (9) | 1,192 (5) | 1,872 (7) | 1,050 (4) | 16,234 (64) | 25,433 |