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. 2025 Aug 21;16:15. doi: 10.1186/s13326-025-00337-2

Table 6.

Manual validation of best mapping found using the Rosetta stone and UMLS service. We randomly selected 10 examples for each penalty score 0.0 (exact), 0.1 (MedDRA traversal from LLT to PT), and 1.0 (hierarchical traversal in SNOMED CT) and checked if the MedDRA terms were the semantically best matches

Source Target N Score Best Match Rosetta Stone (%) Best Match UMLS (%)
HPATH/MA MedDRA 10 0.0 10 (100.0) 5 (50.0)
HPATH/MA MedDRA 10 0.1 8 (80.0) 2 (20.0)
HPATH/MA MedDRA 10 1.0 9 (90.0) 1 (10.0)
SEND MedDRA 10 0.0 10 (100.0) 3 (0.30)
SEND MedDRA 10 0.1 10 (100.0) 1 (10.0)
SEND MedDRA 10 1.0 10 (100.0) 1 (10.0)
total 60 57 (95.0) 13 (21.7)