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. 2025 Aug 21;24:344. doi: 10.1186/s12933-025-02902-6

Table 2.

Complex survey-weighted regression analysis of TyG-ABSI and risks of CVD, cardiovascular mortality, and all-cause mortality

Exposure Outcome Model 1 Model 2 Model 3
OR(95%CI) P-value OR(95%CI) p-value OR(95%CI) p-value
TyG-ABSI CVD 1.89 (1.73 ~ 2.06) < 0.001 1.39 (1.25 ~ 1.55) < 0.001 1.28 (1.15 ~ 1.43) < 0.001
TyG-ABSI tertile
T1 (lowest) Reference Reference Reference
T2 (middle) 1.77 (1.48 ~ 2.12) < 0.001 1.23 (1.00 ~ 1.50) 0.048 1.09 (0.89 ~ 1.35) 0.396
T3 (highest) 3.19 (2.66 ~ 3.82) < 0.001 1.75 (1.43 ~ 2.14) < 0.001 1.48 (1.20 ~ 1.83) < 0.001
P for trend < 0.001 < 0.001 < 0.001
HR(95%CI) P-value HR(95%CI) p-value HR(95%CI) p-value
TyG-ABSI Cardiovascular mortality 1.83 (1.63 ~ 2.06) < 0.001 1.26 (1.10 ~ 1.47) 0.003 1.25 (1.08 ~ 1.45) 0.003
TyG-ABSI tertile
T1 (lowest) Reference Reference Reference
T2 (middle) 1.99 (1.46 ~ 2.71) < 0.001 1.18 (0.87 ~ 1.62) 0.288 1.25 (0.90 ~ 1.73) 0.193
T3 (highest) 3.11 (2.35 ~ 4.12) < 0.001 1.37 (1.01 ~ 1.85) 0.043 1.40 (1.02 ~ 1.92) 0.036
P for trend < 0.001 0.037 0.032
TyG-ABSI All-cause mortality 1.85 (1.72 ~ 1.98) < 0.001 1.30 (1.20 ~ 1.42) < 0.001 1.28 (1.16 ~ 1.40) < 0.001
TyG-ABSI tertile
T1 (lowest) Reference Reference Reference
T2 (middle) 1.71 (1.43 ~ 2.05) < 0.001 1.06 (0.89 ~ 1.27) 0.514 1.08 (0.88 ~ 1.31) 0.478
T3 (highest) 2.92 (2.52 ~ 3.38) < 0.001 1.37 (1.17 ~ 1.60) < 0.001 1.34 (1.11 ~ 1.61) 0.002
P for trend < 0.001 < 0.001 < 0.001

Model 1: No adjustment; Model 2: Adjusted for age, gender, and race; Model 3: Additionally adjusted for marital status, education, PIR, smoking, alcohol use, cancer, CKD, BMI, total energy intake, TC, LDL-C, BUN, UA, Cr, ALT, AST, ALB, TBil, antidiabetic medication use, statin use, antihypertensive use