Table 2.
Complex survey-weighted regression analysis of TyG-ABSI and risks of CVD, cardiovascular mortality, and all-cause mortality
| Exposure | Outcome | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|---|
| OR(95%CI) | P-value | OR(95%CI) | p-value | OR(95%CI) | p-value | ||
| TyG-ABSI | CVD | 1.89 (1.73 ~ 2.06) | < 0.001 | 1.39 (1.25 ~ 1.55) | < 0.001 | 1.28 (1.15 ~ 1.43) | < 0.001 |
| TyG-ABSI tertile | |||||||
| T1 (lowest) | Reference | Reference | Reference | ||||
| T2 (middle) | 1.77 (1.48 ~ 2.12) | < 0.001 | 1.23 (1.00 ~ 1.50) | 0.048 | 1.09 (0.89 ~ 1.35) | 0.396 | |
| T3 (highest) | 3.19 (2.66 ~ 3.82) | < 0.001 | 1.75 (1.43 ~ 2.14) | < 0.001 | 1.48 (1.20 ~ 1.83) | < 0.001 | |
| P for trend | < 0.001 | < 0.001 | < 0.001 | ||||
| HR(95%CI) | P-value | HR(95%CI) | p-value | HR(95%CI) | p-value | ||
| TyG-ABSI | Cardiovascular mortality | 1.83 (1.63 ~ 2.06) | < 0.001 | 1.26 (1.10 ~ 1.47) | 0.003 | 1.25 (1.08 ~ 1.45) | 0.003 |
| TyG-ABSI tertile | |||||||
| T1 (lowest) | Reference | Reference | Reference | ||||
| T2 (middle) | 1.99 (1.46 ~ 2.71) | < 0.001 | 1.18 (0.87 ~ 1.62) | 0.288 | 1.25 (0.90 ~ 1.73) | 0.193 | |
| T3 (highest) | 3.11 (2.35 ~ 4.12) | < 0.001 | 1.37 (1.01 ~ 1.85) | 0.043 | 1.40 (1.02 ~ 1.92) | 0.036 | |
| P for trend | < 0.001 | 0.037 | 0.032 | ||||
| TyG-ABSI | All-cause mortality | 1.85 (1.72 ~ 1.98) | < 0.001 | 1.30 (1.20 ~ 1.42) | < 0.001 | 1.28 (1.16 ~ 1.40) | < 0.001 |
| TyG-ABSI tertile | |||||||
| T1 (lowest) | Reference | Reference | Reference | ||||
| T2 (middle) | 1.71 (1.43 ~ 2.05) | < 0.001 | 1.06 (0.89 ~ 1.27) | 0.514 | 1.08 (0.88 ~ 1.31) | 0.478 | |
| T3 (highest) | 2.92 (2.52 ~ 3.38) | < 0.001 | 1.37 (1.17 ~ 1.60) | < 0.001 | 1.34 (1.11 ~ 1.61) | 0.002 | |
| P for trend | < 0.001 | < 0.001 | < 0.001 | ||||
Model 1: No adjustment; Model 2: Adjusted for age, gender, and race; Model 3: Additionally adjusted for marital status, education, PIR, smoking, alcohol use, cancer, CKD, BMI, total energy intake, TC, LDL-C, BUN, UA, Cr, ALT, AST, ALB, TBil, antidiabetic medication use, statin use, antihypertensive use