Table 2.
Logistic regression of factors associated with clotting-related premature termination of IRRT
| Index | Univariate | Multivariate | ||
|---|---|---|---|---|
| OR (95%CI) | P value | OR (95%CI) | P value | |
| Age (year) | 1.008(0.990–1.029) | 0.355 | 1.016(0.992–1.041) | 0.211 |
| Male Gender | 1.536(0.766–3.102) | 0.227 | 1.519(0.629–3.748) | 0.356 |
| AKI | 1.582(0.788–3.221) | 0.200 | 1.185(0.5052–2.798) | 0.697 |
| eGFR(ml/min/1.73m2) | 0.962(0.904–1.013) | 0.177 | 0.966(0.905–1.020) | 0.237 |
| Hemoglobin (g/dl) | 1.445(1.178–1.807) | < 0.001 | 1.482(1.180–1.914) | 0.001 |
| Hypertension | 1.865(0.725–5.446) | 0.218 | ||
| Diabetes mellitus | 1.287(0.408–3.808) | 0.652 | ||
| Liver disease | 0.933(0.239–3.135) | 0.914 | ||
| Warfarin use | 0.758(0.229–2.188) | 0.623 | ||
| Anti-platelet drugs | 1.500(0.569–3.842) | 0.400 | ||
| R(min) | 0.992(0.810–1.201) | 0.933 | ||
| MA(mm) | 1.007(0.972–1.046) | 0.693 | ||
| K(min) | 0.938(0.640–1.254) | 0.689 | ||
| α-angle(deg) | 1.002(0.963–1.044) | 0.940 | ||
| Platelet count (109/dl) | 1.045(1.000-1.094) | 0.056 | 1.072(1.014–1.137) | 0.015 |
| APTT(s) | 1.033(0.937–1.067) | 0.919 | ||
| INR | 1.427(0.591–5.068) | 0.435 | ||
| Fibrinogen (g/L) | 1.074(0.810–1.419) | 0.616 | ||
| Serum albumin (g/L) | 1.007(0.954–1.063) | 0.796 | ||
| Choice of anticoagulation | ||||
| Heparin-free (reference) | reference | reference | ||
| RCA | 0.166(0.059–0.403) | < 0.001 | 0.121(0.037–0.332) | < 0.001 |
| Delivered blood flow rate (ml/min) | ||||
| 210–220 | reference | |||
| 180–200 | 2.469 (0.914–7.018) | 0.080 | ||
| 230–260 | 0.635 (0.238–1.741) | 0.366 | ||
| Delivered dialysate flow rate (ml/min) | 0.450 (0.066–1.890) | 0.326 | ||
hb: hemoglobin; ALB: serum albumin; APTT: plasma activated partial prothrombin time; PT: prothrombin time; R: reaction time; MA: maximal amplitude; PLT: platelet count; OR: odds ratio; CI: confidence interval; IRRT: intermittent renal replacement therapy