Table 1.
Sample description
| Autistic individuals | Non-autistic individuals | Group diff. (p) | |
|---|---|---|---|
| n | 140 | 98 | – |
| Gender (M/F) | 105/35 | 61/37 | 0.049 |
| Timepoints (1/2/1 + 2) | 41/48/51 | 27/36/35 | 0.92 |
| Age (in years) | 16.15/5.51 [6.24–29.23] | 17.43/5.96 [6.24–30.98] | 0.093 |
| IQ | 98.32/21.18 [46–148] | 104.51/21.12 [50–142] | 0.028 |
| Perceptual IQ | 99.58/21.05 [46–138] | 104.19/20.96 [49–147] | 0.097 |
| Verbal IQ | 96.58/20.7 [45–160] | 103.3/20.92 [51–160] | 0.016 |
| Missing data per trial (%) | 15.89/17.17 [0.77–99.98] | 13.19/14.02 [0.41–73.94] | 0.184 |
| Sampling rate (300 Hz / 120 Hz) | 127/72 | 89/44 | 0.644 |
| Gaze center deviation (%) | 18.33/2.43 [13.39–26.9] | 17.89/2.3 [13.42–25.79] | 0.157 |
| Mean pupil size (mm) | 3.52/0.51 [2.32–4.82] | 3.36/0.55 [2.28–5.9] | 0.023 |
| Medication (yes/no) | 65/75 | 20/78 | < 0.001 |
| SRS (total) | 100.47/29.75 [20–168] | 30.58/30.67 [1–113] | < 0.001 |
| RBS (total) | 20.67/16.08 [0–90] | 2.93/5.97 [0–34] | < 0.001 |
| SDQ (total) | 17.69/6.4 [3–34] | 9.3/8.24 [0–30] | < 0.001 |
| ADHD inattention | 5.18/3.25 [0–9] | 1.78/2.72 [0–9] | < 0.001 |
| ADHD hyperactivity | 3.24/3.02 [0–9] | 1/2.03 [0–9] | < 0.001 |
| BAI (anxiety) | 15.26/11.36 [0–63] | 9.58/8.27 [0–38] | < 0.001 |
| BDI (depression) | 13.64/11.44 [0–61] | 9.05/9.31 [0–39] | < 0.001 |
Total numbers are provided for individuals (n), gender, medication, and timepoints. Other variables are described by the statistics: mean / standard deviation [min – max]. Supplementary Note 1 provides further information on the type of medication. perceptual IQ = a non-verbal IQ estimate based on the block design and matrix reasoning subtests of the age-appropriate Wechsler Intelligence Scale (WAIS-IV, WISC-IV); verbal IQ = a verbal IQ estimate based on the similarities and vocabulary subtests of the age-appropriate Wechsler Intelligence Scale (WAIS-IV, WISC-IV); SRS = Social Responsiveness Scale; RBS = Repetitive Behavior Scale; SDQ = Strengths and Difficulties Questionnaire; ADHD = ADHD rating scale DSM-5; BAI = Beck’s Anxiety Inventory; BDI = Beck’s Depression Inventory. Further information on all measures is provided in the clinical characterization of the EU-AIMS LEAP data set [38].