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. 2025 Aug 21;25:804. doi: 10.1186/s12888-025-07269-2

Table 1.

Sample demographics and clinical characteristics of the study population and differences among the5 clusters(281dyads)

Patient variables Total
(n = 281)
Cluster 1
(n = 52)
Cluster 2
(n = 29)
Cluster 3
(n = 130)
Cluster 4
(n = 32)
Cluster5
(n = 38)
Statistic p-value
General characteristics of patients
Age(years), M ± SD 14.74 ± 1.77 14.54 ± 1.90 14.86 ± 1.87 14.85 ± 1.76 14.75 ± 1.93 14.50 ± 1.37 0.510* 0.728
Gender, n(%) 5.657# 0.226
 Male 77(27.40) 20(38.50) 6(20.70) 33(25.40) 6(18.80) 12(31.60)
 Female 204(72.60) 32(61.50) 23(79.30) 97(74.60) 26(81.30) 26(68.40)
Education, n(%) 2.174# 0.704
 Middle school and below 189(67.30) 35 (67.30) 20 (69.00) 83 (63.80) 22 (68.80) 29 (76.30)
 High school 92(32.70) 17 (32.70) 9 (31.00) 47 (36.20) 10 (31.30) 9 (23.70)
Number of children, n(%) 8.219# 0.084
 One 144(51.20) 24(46.20) 18(62.10) 59(45.40) 17(53.10) 26(68.40)
 More than one 137(48.80) 28(53.80) 11(37.90) 71(54.60) 15(46.90) 12(31.60)
Payment type for medical expenses, n(%) 10.820# 0.029
 Self-financed 89(31.70) 22(42.30)a 3(10.30)b 43(33.10)a, b 7(21.90)a, b 14(36.80)a, b
 Medical insurance 192(68.30) 30(57.70)a 26(89.70)b 87(66.90)a, b 25(78.10)a, b 24(63.20)a, b
Time since diagnosisd,n(%) 15.843c 0.172
 1-6month 137(48.80) 25 (48.10) 16 (55.20) 63 (48.50) 18 (56.30) 15 (39.50)
 7-18month 94(33.50) 21 (40.40) 8 (27.60) 46 (35.40) 10 (31.30) 9 (23.70)
 19-36month 30(10.70) 4 (7.70) 3 (10.30) 11 (8.50) 1 (3.10) 11(28.90)
 > 36month 20(7.10) 2 (3.80) 2 (6.90) 10 (7.70) 3 (9.40) 3 (7.90)
Self-injurious behavior, n(%) 1.738# 0.784
 No 89(31.70) 20(38.50) 8(27.60) 39(30.00) 11(34.40) 11(28.90)
 Yes 192(68.30) 32(61.50) 21(72.40) 91(70.00) 21(65.50) 27(71.10)
History of psychiatric medication self-discontinuation, n(%) 11.406# 0.022
 No 153(54.40) 25(48.10)a, b 17(58.60)a, b 73(56.20)a, b 24(75.00)b 14(36.80)a
 Yes 128(45.60) 27(51.90)a, b 12(41.40)a, b 57(43.80)a, b 8(25.00)b 24(63.20)a
Current presence of disease-related distress, n(%) 47.235# < 0.001
 No 44(15.70) 3(5.80)a 5(17.20)a 15(11.50)a 18(56.30)b 3(7.90)a
 Yes 237(84.30) 49(94.20)a 24(82.80)a 115(88.50)a 14(43.80)b 35(92.10)a
Perceived parent-child relationship, n(%) 82.211# < 0.001
 Poor 31(11.10) 1(1.90)a 1(3.40)a 9(6.90)a 2(6.30)a 18(47.40)b
 Average 105(37.40) 30(57.70)a 10(34.50)a, b 47(36.20)a, b 4(12.50)b 14(36.80)a, b
 Perfect 145(51.60) 21(40.40)a, b 18(62.10)b, c 74(56.90)b, c 26(81.30)c 6(15.80)a
General characteristics of Caregiver
 Relationship, n(%) 2.700# 0.609
  Mother 212(75.40) 43(82.70) 20(69.00) 97(74.60) 25(78.10) 27(71.10)
  Father 69(24.60) 9(17.30) 9(31.00) 33(25.40) 7(21.90) 11(28.90)
  Age(years), M ± SD 43.12 ± 4.92 43.75 ± 5.47 42.34 ± 4.64 42.81 ± 4.76 43.09 ± 5.61 43.95 ± 4.3 0.789* 0.533
 Education, n(%) 13.808# 0.087
  Middele school and below 85(30.20) 17(32.70) 4(13.80) 41(31.50) 7(21.90) 16(42.10)
  High school 42(14.90) 5(9.60) 5(17.20) 23(17.70) 2(6.30) 7(18.40)
  Bachelor or above 154(54.80) 30(57.70) 20(69.00) 66(50.80) 23(71.90) 15(39.50)
 Employment, n(%) 17.558& 0.020
  Full-time or Part-time 172(61.20) 31 (59.60)a, b 10(34.50)b 84 (64.60)a 19 (59.40)a, b 28 (73.70)a
  Self-employed 84(29.90) 13 (25.00)a, b 16(55.20)b 38 (29.20)a, b 11 (34.40)a, b 6 (15.80)a
  Unemployed 25(8.90) 8 (15.40)a 3 (10.30)a 8 (6.20)a 2 (6.30)a 4 (10.50)a
 Family location, n(%) 3.027& 0.553
  Urban areas 245(87.20) 46 (88.50) 28 (96.60) 110 (84.60) 28 (87.50) 33 (86.80)
  Rural areas 36(12.80) 6 (11.50) 1 (3.40) 20 (15.40) 4 (12.50) 5 (13.20)
 Family types, n(%) 12.289& 0.402
  Core family 159(56.60) 31 (59.60) 14 (48.30) 77 (59.20) 20 (62.50) 17 (44.70)
  Extended family 77(27.40) 9 (17.30) 8 (27.60) 38 (29.20) 8 (25.00) 14 (36.80)
  Stepparent family 22(7.80) 5 (9.60) 3 (10.30) 8 (6.20) 3 (9.40) 3 (7.90)
  Single-parent family 23(8.20) 7 (13.50) 4 (13.80) 7 (5.40) 1 (3.10) 4 (10.50)
 Per capita monthly household income(yuan)e,n(%) 23.126# 0.003
  ≤ 4000 81(28.80) 22(42.30)a 7(24.10)a, b 32(24.60)a, b 4(12.50)b 16(42.10)a, b
  4001 ~ 8000 97(34.50) 10(19.20)a 6(20.70)a, b 51(39.20)a, b 16(50.00)b 14(36.80)a, b
  >8000 103(36.70) 20(38.50)a, b 16(55.20)b 47(36.20)a, b 12(37.50)a, b 8(21.10)a
 Parenting Style, n(%) 27.371# 0.007
  Authoritarian 53(18.90) 14(26.90)a 7(24.10)a 23(17.70)a 6(18.80)a 3(7.90)a
  Neglectful 38(13.50) 12(23.10)a, b 1(3.40)a, b 13(10.00)b 1(3.10)b 11(28.90)a
  Permissive 124(44.10) 20(38.50)a 12(41.40)a 58(44.60)a 18(56.30)a 16(42.10)a
  Authoritative 66(23.50) 6(11.50)a 9(31.00)a 36(27.70)a 7(21.90)a 8(21.10)a
 Perceived parent-child relationship, n(%) 20.622& 0.006
  Poor 24(8.50) 4(7.70)a 0(0.00)a 13(10.00)a 1(3.10)a 6(15.80)a
  Average 91(32.40) 24(46.20)a 3(10.30)b 42(32.30)a, b 9(28.10)a, b 13(34.20)a, b
  Good 166(59.10) 24(46.20)a 26(89.70)b 75(57.70)a 22(68.80)a, b 19(50.00)a
 Perceived spousal relationship (total n = 254),n(%) 23.772& 0.001
  Poor 12(4.70) 2(4.30)a, b 1(4.00)a, b 3(2.50)b 1(3.60)a, b 5(15.20)a
  Average 72(28.30) 21(44.70)a 1(4.00)b 32(26.40)a, b 7(25.00)a, b 11(33.30)a, b
  Good 170(66.90) 24(51.10)a 23(92.00)b 86(71.10)a, b 20(71.40)a, b 17(51.50)a

a, b,cProportions in the same row with different superscript letters indicate significant differences between groups (p < 0.05, Bonferroni-adjusted)

dTime since diagnosis was used to measure the duration of the disease, calculated from the date of formal diagnosis to the date of the survey

e4000 Chinese Yuan ≈ 562.688 US dollar; and the national per capita disposable annual income of Chinese residents in 2023 was 39,218 Chinese Yuan (https://www.stats.gov.cn/sj/zxfb/202401/t20240116_1946622.html)

*One-Way ANOVA

#Pearson chi-square test

&Fisher’s exact test