Table 3.

The association between cardiometabolic phenotypes and AIP in the Azar cohort population

	AIP Risk levels	MUHNW		MHO		MUHO
		OR (95%CI)	P	OR (95%CI)	P	OR (95%CI)	P
Cardiometabolic phenotypes (9515)	Low Risk	Reference		Reference		Reference
Model 1	Intermediate Risk	5.12 (2.15–12.18)	< 0.001	1.39(1.19–1.62)	< 0.001	5.33(4.43–6.41)	< 0.001
	High Risk	40.68(21.38–77.39)	< 0.001	1.55(1.33–1.80)	< 0.001	19.41(16.44–22.91)	< 0.001
Model 2	Low Risk	Reference		Reference		Reference
	Intermediate Risk	6.04 (2.53–14.42)	< 0.001	1.52(1.30–1.79)	< 0.001	6.40(5.27–7.77)	< 0.001
	High Risk	63.49(32.89–122.56)	< 0.001	1.96(1.67–2.31)	< 0.001	32.15(26.73–38.66)	< 0.001
Male (3970)	Low Risk	Reference		Reference		Reference
Model 1	Intermediate Risk	4.23(0.59–30.22)	0.15	1.80(1.46–2.20)	< 0.001	5.23(3.61–7.58)	< 0.001
	High Risk	79.15(19.01–329.54)	< 0.001	2.86(2.37–3.44)	< 0.001	40.73(30.13–55.05)	< 0.001
Model 2	Low Risk	Reference		Reference		Reference
	Intermediate Risk	4.74(0.66–34.00)	0.12	1.84(1.50–2.27)	< 0.001	5.49(3.77–8.00)	< 0.001
	High Risk	101.26(24.10–425.35)	< 0.001	2.98(2.46–3.61)	< 0.001	46.43(34.05–63.33)	< 0.001
Female (5545)	Low Risk	Reference		Reference		Reference
Model 1	Intermediate Risk	7.84(2.93–20.90)	< 0.001	1.55(1.20–2.01)	< 0.001	7.97(6.06–10.46)	< 0.001
	High Risk	49.87(23.04–107.93)	< 0.001	1.01(0.74–1.37)	0.93	28.09(21.04–37.50)	< 0.001
Model 2	Low Risk	Reference		Reference		Reference
	Intermediate Risk	8.40(3.13–22.54)	< 0.001	1.59(1.22–2.06)	< 0.001	8.73(6.58–11.57)	< 0.001
	High Risk	63.17(28.81–138.48)	< 0.001	1.08(0.79–1.47)	0.6	35.69(26.38–48.27)	< 0.001

AIP Atherogenic Index of Plasm, OR Odd ratio, CI confidence interval, MUHNW Metabolically Unhealthy Normal Weight, MHO Metabolically Healthy Obese, MUHO Metabolically Unhealthy Obese

Model 1: Unadjusted

Model 2: Adjusted model for age, METs, WSI, and Smoking status