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. 2025 Jul 23;17(7):e88575. doi: 10.7759/cureus.88575

Figure 3. Polymorphous low-grade neuroepithelial tumor of the young, CNS WHO Grade 1.

Figure 3

(A) T1-weighted imaging (T1WI) shows hypointensity. (B) T2-weighted imaging (T2WI) demonstrates hyperintensity with a “salt and pepper” appearance. (C) Histologically, the tumor consists of oligodendroglioma-like cells with interspersed thin-walled capillary channels (H&E, 20x). (D) Abundant microcalcifications are present within the lesion (H&E, 10x). (E) Tumor cells show intense and widespread CD34 immunopositivity (CD34, 4x). (F) BRAF V600E mutation is expressed in neoplastic cells (BRAF V600E, 40x).

Image Source: Fabbri et al. [40] shared under the under a CC-BY-NC-ND 4.0 International License.