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. 2025 Aug 21;57(1):2546681. doi: 10.1080/07853890.2025.2546681
Parasitic myoma
Clinical presentations Diagnostic tools Differential diagnosis Treatment modalities Follow-up
Symptoms
  • Abdominal/ pelvic pain (most common)

  • Compression of adjacent organs

  • Dysmenorrhea


Signs
  • Pelvic mass

  • Abdominal distension

  • Vaginal bleeding


Asymptomatic
<10% of cases
Abdominal US and/or TVUS
Initial evaluation but limited specificity
Pelvic MRI
Preferred for better characterize extent, and consistency
Abdominal CT
To assess the extent, to exclude the presence of other abdominal lesions
PET-CT/MRI
If malignancy is suspected
Histopathology
To obtain definitive diagnosis
Ovarian lesions
Leiomyosarcoma
Peritoneal carcinomatosis
Endometriosis with deep infiltration
GISTs
Peritoneal tuberculosis
Sarcomatosis
Multidisciplinary discussion
To determine the best therapeutical approach, the potential surgical radicality, and patient’s operability
Debulking surgery
Most effective
LPT vs. LPS
Depending on position, and size of lesion
Morcellation
It should be avoided, containment bags should be used
Hormonal treatment
It should be considered in case of patients unfit for surgery or as maintenance therapy after surgery
Not-well defined
TVUS and/or RMI
To evaluate regression, progression, or recurrence
Re-excision
It may be considered in case of residual lesions, or recurrences
US: ultrasound; TVUS: trans-vaginal ultrasound; MRI: magnetic resonance imaging; CT: computed tomography; PET: positron emission tomography; GISTs: gastrointestinal stromal tumors; LPT: laparotomy; LPS: laparoscopy.